Oxytocin and Addiction - A Review
Kovács GL, Sarnyai Z, Szabó G. · Psychoneuroendocrinology · 1998
Original publication · Original publication
Attributed extracts from the research record
“OXT receptors in the CNS—mainly those located in limbic and basal forebrain structures—are responsible for mediating various effects of OXT in the opiate- and cocaine-addicted organism.”
“Tolerance to ethanol (e.g. hypothermia-inducing effect of ethanol) also was inhibited by OXT.”
“In relation to cocaine abuse, OXT dose-dependently decreased cocaine-induced hyperlocomotion and stereotyped grooming behavior.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/9924746/ · https://doi.org/10.1016/s0306-4530(98)00064-x · https://www.sciencedirect.com/science/article/abs/pii/S030645309800064X
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- sound:xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- sound
- trust Score
- 1
- key
- general:sound-xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- general
- trust Score
- 1
Citation snapshot and identifiers
- id
- pmid-9924746
- doi
- 10.1016/s0306-4530(98)00064-x
- pmid
- 9924746
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- 265
- general
- 265
Complete approved library record
- id
- pmid-9924746
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Oxytocin and Addiction - A Review
- journal
- Psychoneuroendocrinology
- neurotransmitters
- None recorded
- year
- 1998
- authors
- Kovács GL, Sarnyai Z, Szabó G.
- design
- kind
- Review / synthesis
- identity Conflict
- Not recorded
- doi
- 10.1016/s0306-4530(98)00064-x
- pmid
- 9924746
- urls
https://doi.org/10.1016/s0306-4530(98)00064-x · https://pubmed.ncbi.nlm.nih.gov/9924746/
- collections
sound · general
- categories
Molecular biomarkers · Brain & nervous system
- targets
OXT
- priority
- 1
- quotes
“OXT receptors in the CNS—mainly those located in limbic and basal forebrain structures—are responsible for mediating various effects of OXT in the opiate- and cocaine-addicted organism.” · “Tolerance to ethanol (e.g. hypothermia-inducing effect of ethanol) also was inhibited by OXT.” · “In relation to cocaine abuse, OXT dose-dependently decreased cocaine-induced hyperlocomotion and stereotyped grooming behavior.”
- summary
- limitation
- citation Count
- 265
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/9924746/ · https://doi.org/10.1016/s0306-4530(98)00064-x · https://www.sciencedirect.com/science/article/abs/pii/S030645309800064X
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 265
- general
- 265
- topics
- key
- sound:xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- sound
- trust Score
- 1
- key
- general:sound-xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- general
- trust Score
- 1
- journal Key
- psychoneuroendocrinology
- journal Label
- Psychoneuroendocrinology
- chapter Entries
- id
- xxix-pmid-9924746
- record Id
- pmid-9924746
- title
- Oxytocin and Addiction - A Review
- journal
- Psychoneuroendocrinology
- year
- 1998
- authors
- Kovács GL, Sarnyai Z, Szabó G.
- design
- urls
https://doi.org/10.1016/s0306-4530(98)00064-x · https://pubmed.ncbi.nlm.nih.gov/9924746/
- quotes
- text
- “OXT receptors in the CNS—mainly those located in limbic and basal forebrain structures—are responsible for mediating various effects of OXT in the opiate- and cocaine-addicted organism.”
- emphasis
- false
- text
- “Tolerance to ethanol (e.g. hypothermia-inducing effect of ethanol) also was inhibited by OXT.”
- emphasis
- false
- text
- “In relation to cocaine abuse, OXT dose-dependently decreased cocaine-induced hyperlocomotion and stereotyped grooming behavior.”
- emphasis
- false
- citation Count
- 265
- source Pages
118
- targets
OXT
- categories
Molecular biomarkers · Brain & nervous system
- doi
- 10.1016/s0306-4530(98)00064-x
- pmid
- 9924746
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/9924746/ · https://doi.org/10.1016/s0306-4530(98)00064-x · https://www.sciencedirect.com/science/article/abs/pii/S030645309800064X
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- sound
- chapter Number
- 6
- topic Id
- xxix
- topic Title
- Oxytocin pathways, dopamine and serotonin
- trust Score
- 1
- id
- general-xxix-pmid-9924746
- record Id
- pmid-9924746
- title
- Oxytocin and Addiction - A Review
- journal
- Psychoneuroendocrinology
- year
- 1998
- authors
- Kovács GL, Sarnyai Z, Szabó G.
- design
- urls
https://doi.org/10.1016/s0306-4530(98)00064-x · https://pubmed.ncbi.nlm.nih.gov/9924746/
- quotes
- text
- “OXT receptors in the CNS—mainly those located in limbic and basal forebrain structures—are responsible for mediating various effects of OXT in the opiate- and cocaine-addicted organism.”
- emphasis
- false
- text
- “Tolerance to ethanol (e.g. hypothermia-inducing effect of ethanol) also was inhibited by OXT.”
- emphasis
- false
- text
- “In relation to cocaine abuse, OXT dose-dependently decreased cocaine-induced hyperlocomotion and stereotyped grooming behavior.”
- emphasis
- false
- citation Count
- 265
- source Pages
118
- targets
OXT
- categories
Molecular biomarkers · Brain & nervous system
- doi
- 10.1016/s0306-4530(98)00064-x
- pmid
- 9924746
- paper Trust Assessment
- score
- 1
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- false
- blinding
- not-applicable
- peer Reviewed
- true
- basis
- Indexed peer-reviewed research; a qualifying randomized controlled design is not established in the reviewed record.
- sources
https://pubmed.ncbi.nlm.nih.gov/9924746/ · https://doi.org/10.1016/s0306-4530(98)00064-x · https://www.sciencedirect.com/science/article/abs/pii/S030645309800064X
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- general
- chapter Number
- 1
- topic Id
- sound-xxix
- topic Title
- Oxytocin pathways, dopamine and serotonin
- trust Score
- 1
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- id
- substance-use
- evidence
- field
- title
- text
- Oxytocin and Addiction - A Review
- matched Text
- Addiction
- conditions
substance-use
- topic Trust Scores
1
- full Text
- status
- not-indexed
- retrieval Available
- false