Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators
Scientific Reports
Original publication · Original publication
Attributed extracts from the research record
“Our data provided important insights into one of the mechanisms by which H2 regulates signal transduction and gene expression; however, H2 might contribute to other types of signaling pathways as well because H2 regulates many genes belonging to various signaling pathways.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.nature.com/articles/srep18971
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- language:vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
- collection
- language
- trust Score
- 3
- key
- general:language-vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
- collection
- general
- trust Score
- 3
Citation snapshot and identifiers
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- src-073eaac7c1c6
- doi
- 10.1038/srep18971
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- citations By Collection
- language
- 72
- general
- 72
Complete approved library record
- id
- src-073eaac7c1c6
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators
- journal
- Scientific Reports
- publisher Family
- nature
- publisher Family Label
- Nature Portfolio
- neurotransmitters
- None recorded
- year
- Not recorded
- authors
- design
- kind
- Source record
- identity Conflict
- Not recorded
- doi
- 10.1038/srep18971
- urls
https://www.nature.com/articles/srep18971 · https://doi.org/10.1038/srep18971
- collections
language · general
- categories
Gene expression
- targets
- None recorded
- priority
- 0
- quotes
“Our data provided important insights into one of the mechanisms by which H2 regulates signal transduction and gene expression; however, H2 might contribute to other types of signaling pathways as well because H2 regulates many genes belonging to various signaling pathways.”
- summary
- limitation
- citation Count
- 72
- paper Trust Assessment
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.nature.com/articles/srep18971
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 72
- general
- 72
- topics
- key
- language:vi
- title
- Molecular hydrogen: inflammation, cognition and gene expression
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- Molecular hydrogen: inflammation, cognition and gene expression
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- Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators
- journal
- Scientific Reports
- year
- Not recorded
- authors
- design
- urls
https://www.nature.com/articles/srep18971 · https://doi.org/10.1038/srep18971
- quotes
- text
- “Our data provided important insights into one of the mechanisms by which H2 regulates signal transduction and gene expression; however, H2 might contribute to other types of signaling pathways as well because H2 regulates many genes belonging to various signaling pathways.”
- emphasis
- false
- citation Count
- 72
- source Pages
28
- targets
- None recorded
- categories
Gene expression
- doi
- 10.1038/srep18971
- pmid
- Not recorded
- paper Trust Assessment
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.nature.com/articles/srep18971
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
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- Molecular hydrogen: inflammation, cognition and gene expression
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- title
- Molecular hydrogen regulates gene expression by modifying the free radical chain reaction-dependent generation of oxidized phospholipid mediators
- journal
- Scientific Reports
- year
- Not recorded
- authors
- design
- urls
https://www.nature.com/articles/srep18971 · https://doi.org/10.1038/srep18971
- quotes
- text
- “Our data provided important insights into one of the mechanisms by which H2 regulates signal transduction and gene expression; however, H2 might contribute to other types of signaling pathways as well because H2 regulates many genes belonging to various signaling pathways.”
- emphasis
- false
- citation Count
- 72
- source Pages
28
- targets
- None recorded
- categories
Gene expression
- doi
- 10.1038/srep18971
- pmid
- Not recorded
- paper Trust Assessment
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.nature.com/articles/srep18971
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- general
- chapter Number
- 3
- topic Id
- language-vi
- topic Title
- Molecular hydrogen: inflammation, cognition and gene expression
- trust Score
- 3
- jadad
- status
- unassessed
- score
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- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
3
- full Text
- status
- open-license
- retrieval Available
- true
- url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4704061/fullTextXML
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- rights
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- http://creativecommons.org/licenses/by/4.0/
- statement
Copyright © 2016, Macmillan Publishers Limited This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
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- e33b1aa9d373e392c1f2a0c12c7da7584277a95220b4feed7f825c19325c56d1
- checked At
- 2026-10-24