The role of oxytocin-dopamine interactions in cocaine-induced locomotor hyperactivity
Neuropharmacology
Attributed extracts from the research record
“Oxytocin, a neurohypophyseal neuropeptide, also partially antagonized cocaine-induced motor hyperactivity.
Moreover, oxytocin antagonized the increased utilization of dopamine, elicited by cocaine in the nucleus accumbens.”
“The data suggest that oxytocin may influence the behavioural effects of cocaine by affecting dopaminergic neurotransmission in some regions of the brain.”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- assessment
- Not recorded
- trust Factor
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.sciencedirect.com/science/article/abs/pii/0028390890900959
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- sound:xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- sound
- trust Score
- 1
- key
- general:sound-xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- general
- trust Score
- 1
Citation snapshot and identifiers
- id
- src-19dff8a8bbe5
- doi
- 10.1016/0028-3908(90)90095-9
- pmid
- Not recorded
- citation Snapshot
- Not recorded
- citations By Collection
- sound
- 128
- general
- 128
Complete approved library record
- id
- src-19dff8a8bbe5
- publication Key
- Not recorded
- aliases
- None recorded
- title
- The role of oxytocin-dopamine interactions in cocaine-induced locomotor hyperactivity
- journal
- Neuropharmacology
- neurotransmitters
- None recorded
- year
- Not recorded
- authors
- design
- kind
- Source record
- identity Conflict
- Not recorded
- doi
- 10.1016/0028-3908(90)90095-9
- urls
https://doi.org/10.1016/0028-3908(90)90095-9
- collections
sound · general
- categories
Molecular biomarkers · Brain & nervous system
- targets
OXT
- priority
- 1
- quotes
“Oxytocin, a neurohypophyseal neuropeptide, also partially antagonized cocaine-induced motor hyperactivity. · Moreover, oxytocin antagonized the increased utilization of dopamine, elicited by cocaine in the nucleus accumbens.” · “The data suggest that oxytocin may influence the behavioural effects of cocaine by affecting dopaminergic neurotransmission in some regions of the brain.”
- summary
- limitation
- citation Count
- 128
- paper Trust Assessment
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.sciencedirect.com/science/article/abs/pii/0028390890900959
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- sound
- 128
- general
- 128
- topics
- key
- sound:xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- sound
- trust Score
- 1
- key
- general:sound-xxix
- title
- Oxytocin pathways, dopamine and serotonin
- collection
- general
- trust Score
- 1
- journal Key
- neuropharmacology
- journal Label
- Neuropharmacology
- chapter Entries
- id
- xxix-src-19dff8a8bbe5
- record Id
- src-19dff8a8bbe5
- title
- The role of oxytocin-dopamine interactions in cocaine-induced locomotor hyperactivity
- journal
- Neuropharmacology
- year
- Not recorded
- authors
- design
- urls
https://doi.org/10.1016/0028-3908(90)90095-9
- quotes
- text
- “Oxytocin, a neurohypophyseal neuropeptide, also partially antagonized cocaine-induced motor hyperactivity.
- emphasis
- false
- text
- Moreover, oxytocin antagonized the increased utilization of dopamine, elicited by cocaine in the nucleus accumbens.”
- emphasis
- false
- text
- “The data suggest that oxytocin may influence the behavioural effects of cocaine by affecting dopaminergic neurotransmission in some regions of the brain.”
- emphasis
- false
- citation Count
- 128
- source Pages
117
- targets
OXT
- categories
Molecular biomarkers · Brain & nervous system
- doi
- 10.1016/0028-3908(90)90095-9
- pmid
- Not recorded
- paper Trust Assessment
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.sciencedirect.com/science/article/abs/pii/0028390890900959
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- sound
- chapter Number
- 6
- topic Id
- xxix
- topic Title
- Oxytocin pathways, dopamine and serotonin
- trust Score
- 1
- id
- general-xxix-src-19dff8a8bbe5
- record Id
- src-19dff8a8bbe5
- title
- The role of oxytocin-dopamine interactions in cocaine-induced locomotor hyperactivity
- journal
- Neuropharmacology
- year
- Not recorded
- authors
- design
- urls
https://doi.org/10.1016/0028-3908(90)90095-9
- quotes
- text
- “Oxytocin, a neurohypophyseal neuropeptide, also partially antagonized cocaine-induced motor hyperactivity.
- emphasis
- false
- text
- Moreover, oxytocin antagonized the increased utilization of dopamine, elicited by cocaine in the nucleus accumbens.”
- emphasis
- false
- text
- “The data suggest that oxytocin may influence the behavioural effects of cocaine by affecting dopaminergic neurotransmission in some regions of the brain.”
- emphasis
- false
- citation Count
- 128
- source Pages
117
- targets
OXT
- categories
Molecular biomarkers · Brain & nervous system
- doi
- 10.1016/0028-3908(90)90095-9
- pmid
- Not recorded
- paper Trust Assessment
- score
- Not recorded
- scope
- Paper
- status
- unassessed
- randomized Controlled Trial
- Not recorded
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Publication-specific design or publication status remains unconfirmed.
- sources
https://www.sciencedirect.com/science/article/abs/pii/0028390890900959
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- collection
- general
- chapter Number
- 1
- topic Id
- sound-xxix
- topic Title
- Oxytocin pathways, dopamine and serotonin
- trust Score
- 1
- jadad
- status
- unassessed
- score
- Not recorded
- condition Evidence
- None recorded
- conditions
- None recorded
- topic Trust Scores
1
- full Text
- status
- not-indexed
- retrieval Available
- false