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Hemispheric‐synchronisation during anaesthesia: a double‐blind randomised trial using audiotapes for intra‐operative nociception control

Anaesthesia · randomised controlled trial, double blind

Original publication

Attributed extracts from the research record

“In conclusion, our findings demonstrate that patients using intra‐operative Hemi‐Sync tapes whilst undergoing a range of different surgical procedures under standardised general anaesthesia with a laryngeal mask require substantially less fentanyl when compared with controls”
“It is possible that the Hemi‐Sync tapes, used intra‐operatively or with the addition of pre‐ and postoperative tapes, could have longer‐term effects on postoperative recovery, and may even result in cost savings through reduced analgesic requirement and shorter hospital stay.”
“In our study, we found that patients exposed to a Hemi‐Sync audio tape whilst undergoing surgery under ‘light’ general anaesthesia required significantly less analgesia with fentanyl when compared with patients listening to a blank tape or to classical music.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
randomised controlled trial, double blind
assessment
Not recorded
trust Factor
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
false
basis
Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
sources

https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2044.1999.00958.x

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
Citation snapshot and identifiers
id
src-d2427f4063b3
doi
10.1046/j.1365-2044.1999.00958.x
pmid
Not recorded
citation Snapshot
Not recorded
citations By Collection
sound
66
Complete approved library record
id
src-d2427f4063b3
publication Key
Not recorded
aliases
None recorded
title
Hemispheric‐synchronisation during anaesthesia: a double‐blind randomised trial using audiotapes for intra‐operative nociception control
journal
Anaesthesia
neurotransmitters
None recorded
year
Not recorded
authors
design
randomised controlled trial, double blind
kind
Source record
identity Conflict
Not recorded
doi
10.1046/j.1365-2044.1999.00958.x
urls

https://doi.org/10.1046/j.1365-2044.1999.00958.x

collections

sound

categories

Methods & context

targets
None recorded
priority
1
quotes

“In conclusion, our findings demonstrate that patients using intra‐operative Hemi‐Sync tapes whilst undergoing a range of different surgical procedures under standardised general anaesthesia with a laryngeal mask require substantially less fentanyl when compared with controls” · “It is possible that the Hemi‐Sync tapes, used intra‐operatively or with the addition of pre‐ and postoperative tapes, could have longer‐term effects on postoperative recovery, and may even result in cost savings through reduced analgesic requirement and shorter hospital stay.” · “In our study, we found that patients exposed to a Hemi‐Sync audio tape whilst undergoing surgery under ‘light’ general anaesthesia required significantly less analgesia with fentanyl when compared with patients listening to a blank tape or to classical music.”

summary
limitation
citation Count
66
paper Trust Assessment
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
false
basis
Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
sources

https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2044.1999.00958.x

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
66
topics
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
journal Key
anaesthesia
journal Label
Anaesthesia
chapter Entries
  1. id
    i-src-d2427f4063b3
    record Id
    src-d2427f4063b3
    title
    Hemispheric‐synchronisation during anaesthesia: a double‐blind randomised trial using audiotapes for intra‐operative nociception control
    journal
    Anaesthesia
    year
    Not recorded
    authors
    design
    randomised controlled trial, double blind
    urls

    https://doi.org/10.1046/j.1365-2044.1999.00958.x

    quotes
      1. text
        “In conclusion, our findings demonstrate that patients using intra‐operative Hemi‐Sync tapes whilst undergoing a range of different surgical procedures under standardised general anaesthesia with a laryngeal mask require substantially less fentanyl when compared with controls”
        emphasis
        false
      1. text
        “It is possible that the Hemi‐Sync tapes, used intra‐operatively or with the addition of pre‐ and postoperative tapes, could have longer‐term effects on postoperative recovery, and may even result in cost savings through reduced analgesic requirement and shorter hospital stay.”
        emphasis
        false
      1. text
        “In our study, we found that patients exposed to a Hemi‐Sync audio tape whilst undergoing surgery under ‘light’ general anaesthesia required significantly less analgesia with fentanyl when compared with patients listening to a blank tape or to classical music.”
        emphasis
        false
    citation Count
    66
    source Pages

    8

    targets
    None recorded
    categories

    Methods & context

    doi
    10.1046/j.1365-2044.1999.00958.x
    pmid
    Not recorded
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    false
    basis
    Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
    sources

    https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2044.1999.00958.x

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    1
    topic Id
    i
    topic Title
    Brain entrainment, pain, anxiety and heart-rate variability
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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