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Psychophysiological reactivity to auditory Binaural Beats stimulation in the alpha and theta EEG brain-wave frequency bands: A randomized, double–blind and placebo–controlled study in human healthy young adult subjects

Independent University of Madrid, Department of Biological and Health Psychology · randomised controlled trial, double blind

Original publication

Attributed extracts from the research record

“Significant change over time in the parasympathetic parameter HRV–HF power derived from ECG was only found under binaural beats”
“Pre– vs. post saliva samples revealed significant increases only under Placebo in stress–related biomarkers (Cortisol, α –Amylase and Salivary Secretory Immunoglobulin A, SIgA), but not under binaural beats”
“The ability of the binaural beat stimulus to decrease arousal levels and induce/boost altered states of consciousness (ASCs) implies applications in several practical–clinical contexts and calls for further field studies.”

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
randomised controlled trial, double blind
assessment
Not recorded
trust Factor
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
false
basis
Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
sources

https://repositorio.uam.es/handle/10486/663948

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
Citation snapshot and identifiers
id
src-e3b0fd44d504
doi
Not recorded
pmid
Not recorded
citation Snapshot
Not recorded
citations By Collection
sound
3
Complete approved library record
id
src-e3b0fd44d504
publication Key
Not recorded
aliases
None recorded
title
Psychophysiological reactivity to auditory Binaural Beats stimulation in the alpha and theta EEG brain-wave frequency bands: A randomized, double–blind and placebo–controlled study in human healthy young adult subjects
journal
Independent University of Madrid, Department of Biological and Health Psychology
neurotransmitters
None recorded
year
Not recorded
authors
design
randomised controlled trial, double blind
kind
Source record
identity Conflict
Not recorded
doi
Not recorded
urls

https://dialnet.unirioja.es/servlet/tesis?codigo=45360

collections

sound

categories

Molecular biomarkers · Heart rate & autonomic · Brain & nervous system

targets
None recorded
priority
1
quotes

“Significant change over time in the parasympathetic parameter HRV–HF power derived from ECG was only found under binaural beats” · “Pre– vs. post saliva samples revealed significant increases only under Placebo in stress–related biomarkers (Cortisol, α –Amylase and Salivary Secretory Immunoglobulin A, SIgA), but not under binaural beats” · “The ability of the binaural beat stimulus to decrease arousal levels and induce/boost altered states of consciousness (ASCs) implies applications in several practical–clinical contexts and calls for further field studies.”

summary
limitation
citation Count
3
paper Trust Assessment
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
false
basis
Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
sources

https://repositorio.uam.es/handle/10486/663948

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
3
topics
  1. key
    sound:i
    title
    Brain entrainment, pain, anxiety and heart-rate variability
    collection
    sound
    trust Score
    3
journal Key
journal Label
Independent University of Madrid, Department of Biological and Health Psychology
chapter Entries
  1. id
    i-src-e3b0fd44d504
    record Id
    src-e3b0fd44d504
    title
    Psychophysiological reactivity to auditory Binaural Beats stimulation in the alpha and theta EEG brain-wave frequency bands: A randomized, double–blind and placebo–controlled study in human healthy young adult subjects
    journal
    Independent University of Madrid, Department of Biological and Health Psychology
    year
    Not recorded
    authors
    design
    randomised controlled trial, double blind
    urls

    https://dialnet.unirioja.es/servlet/tesis?codigo=45360

    quotes
      1. text
        “Significant change over time in the parasympathetic parameter HRV–HF power derived from ECG was only found under binaural beats”
        emphasis
        false
      1. text
        “Pre– vs. post saliva samples revealed significant increases only under Placebo in stress–related biomarkers (Cortisol, α –Amylase and Salivary Secretory Immunoglobulin A, SIgA), but not under binaural beats”
        emphasis
        false
      1. text
        “The ability of the binaural beat stimulus to decrease arousal levels and induce/boost altered states of consciousness (ASCs) implies applications in several practical–clinical contexts and calls for further field studies.”
        emphasis
        false
    citation Count
    3
    source Pages

    7

    targets
    None recorded
    categories

    Molecular biomarkers · Heart rate & autonomic · Brain & nervous system

    doi
    Not recorded
    pmid
    Not recorded
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    false
    basis
    Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
    sources

    https://repositorio.uam.es/handle/10486/663948

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    1
    topic Id
    i
    topic Title
    Brain entrainment, pain, anxiety and heart-rate variability
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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