Yogic meditation reverses NF- κ B and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial
Psychoneuroendocrinology · randomised controlled trial
Attributed extracts from the research record
“A brief daily yogic meditation intervention may reverse the pattern of increased NF- κ B-related transcription of pro-inflammatory cytokines and decreased IRF1-related transcription of innate antiviral response genes previously observed in healthy individuals confronting a significant life stressor”
Evidence and provenance
Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.
Study design and assessment
- design
- randomised controlled trial
- assessment
- Not recorded
- trust Factor
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://www.sciencedirect.com/science/article/pii/S0306453012002260?via=ihub
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- jadad
- status
- unassessed
- score
- Not recorded
- evidence
- Not recorded
Topics and recorded topic scores
- key
- language:ii
- title
- Meditation, mindfulness and related practices: gene expression and epigenetics
- collection
- language
- trust Score
- 2
Citation snapshot and identifiers
- id
- src-e9b23a765f28
- doi
- 10.1016/j.psyneuen.2012.06.011
- pmid
- Not recorded
- citation Snapshot
- Not recorded
- citations By Collection
- language
- 219
Complete approved library record
- id
- src-e9b23a765f28
- publication Key
- Not recorded
- aliases
- None recorded
- title
- Yogic meditation reverses NF- κ B and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial
- journal
- Psychoneuroendocrinology
- neurotransmitters
- None recorded
- year
- Not recorded
- authors
- design
- randomised controlled trial
- kind
- Source record
- identity Conflict
- Not recorded
- doi
- 10.1016/j.psyneuen.2012.06.011
- urls
https://doi.org/10.1016/j.psyneuen.2012.06.011
- collections
language
- categories
Gene expression · Molecular biomarkers
- targets
- None recorded
- priority
- 0
- quotes
“A brief daily yogic meditation intervention may reverse the pattern of increased NF- κ B-related transcription of pro-inflammatory cytokines and decreased IRF1-related transcription of innate antiviral response genes previously observed in healthy individuals confronting a significant life stressor”
- summary
- limitation
- citation Count
- 219
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://www.sciencedirect.com/science/article/pii/S0306453012002260?via=ihub
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
- citations By Collection
- language
- 219
- topics
- key
- language:ii
- title
- Meditation, mindfulness and related practices: gene expression and epigenetics
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- trust Score
- 2
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- Psychoneuroendocrinology
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- src-e9b23a765f28
- title
- Yogic meditation reverses NF- κ B and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial
- journal
- Psychoneuroendocrinology
- year
- Not recorded
- authors
- design
- randomised controlled trial
- urls
https://doi.org/10.1016/j.psyneuen.2012.06.011
- quotes
- text
- “A brief daily yogic meditation intervention may reverse the pattern of increased NF- κ B-related transcription of pro-inflammatory cytokines and decreased IRF1-related transcription of innate antiviral response genes previously observed in healthy individuals confronting a significant life stressor”
- emphasis
- false
- citation Count
- 219
- source Pages
13
- targets
- None recorded
- categories
Gene expression · Molecular biomarkers
- doi
- 10.1016/j.psyneuen.2012.06.011
- pmid
- Not recorded
- paper Trust Assessment
- score
- 2
- scope
- Paper
- status
- assessed
- randomized Controlled Trial
- true
- blinding
- not-confirmed
- peer Reviewed
- false
- basis
- Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
- sources
https://www.sciencedirect.com/science/article/pii/S0306453012002260?via=ihub
- review Scope
- Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
- assessed At
- 2026-10-27
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- 1
- topic Id
- ii
- topic Title
- Meditation, mindfulness and related practices: gene expression and epigenetics
- trust Score
- 2
- jadad
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- score
- Not recorded
- condition Evidence
- id
- dementia
- evidence
- field
- title
- text
- Yogic meditation reverses NF- κ B and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial
- matched Text
- dementia
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dementia
- topic Trust Scores
2
- full Text
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- false
- url
- https://pmc-oa-opendata.s3.amazonaws.com/PMC3494746.1/PMC3494746.1.xml?md5=e8bfb3b1ff9af561cef0cf0397deeb27
- pmcid
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- https://pmc.ncbi.nlm.nih.gov/tools/pmcaws/
- article Rights
© 2012 Elsevier Ltd. All rights reserved. 2012 This file is available for text mining. It may also be used consistent with the principles of fair use under the copyright law.
- sha256
- 7af261119540be7804e3aae532b67bc324824c5cfe14838429349544805ca9a7
- checked At
- 2026-10-24