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Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans

The Journal of Neuroscience · randomised controlled trial, double blind

Original publication

Attributed extracts from the research record

“Overall these findings provide the first demonstration that OT can facilitate amygdala-dependent, socially reinforced learning and emotional empathy in men.’

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
randomised controlled trial, double blind
assessment
Not recorded
trust Factor
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
false
basis
Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
sources

https://www.jneurosci.org/content/30/14/4999.short

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
jadad
status
unassessed
score
Not recorded
evidence
Not recorded
Topics and recorded topic scores
  1. key
    sound:xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    sound
    trust Score
    3
  2. key
    general:sound-xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    general
    trust Score
    3
Citation snapshot and identifiers
id
src-ef07290a540d
doi
10.1523/jneurosci.5538-09.2010
pmid
Not recorded
citation Snapshot
Not recorded
citations By Collection
sound
832
general
832
Complete approved library record
id
src-ef07290a540d
publication Key
Not recorded
aliases
None recorded
title
Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans
journal
The Journal of Neuroscience
neurotransmitters
None recorded
year
Not recorded
authors
design
randomised controlled trial, double blind
kind
Source record
identity Conflict
Not recorded
doi
10.1523/jneurosci.5538-09.2010
urls

https://doi.org/10.1523/jneurosci.5538-09.2010

collections

sound · general

categories

Molecular biomarkers

targets

OXT

priority
1
quotes

“Overall these findings provide the first demonstration that OT can facilitate amygdala-dependent, socially reinforced learning and emotional empathy in men.’

summary
limitation
citation Count
832
paper Trust Assessment
score
3
scope
Paper
status
assessed
randomized Controlled Trial
true
blinding
double
peer Reviewed
false
basis
Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
sources

https://www.jneurosci.org/content/30/14/4999.short

review Scope
Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
assessed At
2026-10-27
citations By Collection
sound
832
general
832
topics
  1. key
    sound:xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    sound
    trust Score
    3
  2. key
    general:sound-xxxi
    title
    Oxytocin, empathy and intergroup relationships
    collection
    general
    trust Score
    3
journal Key
journalofneuroscience
journal Label
The Journal of Neuroscience
chapter Entries
  1. id
    xxxi-src-ef07290a540d
    record Id
    src-ef07290a540d
    title
    Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans
    journal
    The Journal of Neuroscience
    year
    Not recorded
    authors
    design
    randomised controlled trial, double blind
    urls

    https://doi.org/10.1523/jneurosci.5538-09.2010

    quotes
      1. text
        “Overall these findings provide the first demonstration that OT can facilitate amygdala-dependent, socially reinforced learning and emotional empathy in men.’
        emphasis
        false
    citation Count
    832
    source Pages

    126

    targets

    OXT

    categories

    Molecular biomarkers

    doi
    10.1523/jneurosci.5538-09.2010
    pmid
    Not recorded
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    false
    basis
    Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
    sources

    https://www.jneurosci.org/content/30/14/4999.short

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    sound
    chapter Number
    6
    topic Id
    xxxi
    topic Title
    Oxytocin, empathy and intergroup relationships
    trust Score
    3
  2. id
    general-xxxi-src-ef07290a540d
    record Id
    src-ef07290a540d
    title
    Oxytocin Enhances Amygdala-Dependent, Socially Reinforced Learning and Emotional Empathy in Humans
    journal
    The Journal of Neuroscience
    year
    Not recorded
    authors
    design
    randomised controlled trial, double blind
    urls

    https://doi.org/10.1523/jneurosci.5538-09.2010

    quotes
      1. text
        “Overall these findings provide the first demonstration that OT can facilitate amygdala-dependent, socially reinforced learning and emotional empathy in men.’
        emphasis
        false
    citation Count
    832
    source Pages

    126

    targets

    OXT

    categories

    Molecular biomarkers

    doi
    10.1523/jneurosci.5538-09.2010
    pmid
    Not recorded
    paper Trust Assessment
    score
    3
    scope
    Paper
    status
    assessed
    randomized Controlled Trial
    true
    blinding
    double
    peer Reviewed
    false
    basis
    Randomized controlled design recorded in the publication-specific design or bibliographic indexing.
    sources

    https://www.jneurosci.org/content/30/14/4999.short

    review Scope
    Existing publication-specific assessments and bibliographic indexing; no blanket full-text appraisal.
    assessed At
    2026-10-27
    collection
    general
    chapter Number
    1
    topic Id
    sound-xxxi
    topic Title
    Oxytocin, empathy and intergroup relationships
    trust Score
    3
jadad
status
unassessed
score
Not recorded
condition Evidence
None recorded
conditions
None recorded
topic Trust Scores

3

full Text
status
not-indexed
retrieval Available
false

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