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Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.

Moreno-Alcázar A, Treen D, Valiente-Gómez A, Sio-Eroles A, Pérez V, Amann BL, Radua J. · Frontiers in psychology · 2017 · Systematic review / meta-analysis

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.

Recorded limitations

Small older evidence base, variable bias and populations, and substantial overlap with later reviews; not an additional set of independent trials.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Systematic review / meta-analysis
assessment
category
review
is Randomized Controlled Trial
false
peer Reviewed
true
basis
systematic-review-meta-analysis
masking Roles
Not applicable or not established from inspected methods; no masking inferred
sources

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

review Scope
selected-methods
trust Factor
score
1
display Crosses
1
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
false
peer Reviewed
true
blinding
not-applicable
masking Roles
Not applicable or not established from inspected methods; no masking inferred
basis
systematic-review-meta-analysis
sources

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
jadad
status
not-applicable
score
Not recorded
evidence
evidence Type
Systematic review / meta-analysis
intervention
EMDR versus waiting, usual care, active listening or CBT; searches through January 2017.
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
Eight RCTs, 295 participants.
population
age
Predominantly children/adolescents; one young-women study had mean age 20.9.
age Fit
mixed-overlap
sample
Eight RCTs, 295 participants.
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-29066991
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Not applicable or not established from inspected methods; no masking inferred
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

retrieved At
2026-11-02
Topics and recorded topic scores
  1. key
    vision:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    vision
    trust Score
    2
  2. key
    vision:emdr-youth
    title
    EMDR for youth
    collection
    vision
    trust Score
    2
Citation snapshot and identifiers
id
youth-pmid-29066991
doi
10.3389/fpsyg.2017.01750
pmid
29066991
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
vision
Not recorded
Complete approved library record
lab Relevance
relationship
inspired-by
implication
Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims.
transfer Limit
Component evidence does not establish efficacy of the combined Universal Mind lab model.
institutions
None recorded
institution Evidence
None recorded
research Topics

EMDR

publication Status
pmid
29066991
checked At
2026-11-02T01:32:40.558430+00:00
pub Types

review-article · Review · Journal Article

indexed Notices
None recorded
crossref Updates
None recorded
notice Records
None recorded
scope
Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
notice Summary
Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
randomized Study Unit Id
Not recorded
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-02
assessment
AI assessed; human approved for publication
scope
Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
source Revision
r1-7bcc23cafcaf
source Content Hash
7bcc23cafcaf6ede3ea39f1b291468e2e0e6b85330112f4537d4b40573d781a8
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

retrieved At
2026-11-02
study Family Id
publication-29066991
approaches

EMDR

id
youth-pmid-29066991
aliases
None recorded
title
Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
journal
Frontiers in psychology
neurotransmitters
None recorded
year
2017
authors
Moreno-Alcázar A, Treen D, Valiente-Gómez A, Sio-Eroles A, Pérez V, Amann BL, Radua J.
design
Systematic review / meta-analysis
kind
Review
identity Conflict
Not recorded
doi
10.3389/fpsyg.2017.01750
pmid
29066991
urls

https://doi.org/10.3389/fpsyg.2017.01750 · https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

collections

vision

categories

Methods & context

targets
None recorded
priority
1
quotes
None recorded
summary
EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
limitation
Small older evidence base, variable bias and populations, and substantial overlap with later reviews; not an additional set of independent trials.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
review
is Randomized Controlled Trial
false
peer Reviewed
true
basis
systematic-review-meta-analysis
masking Roles
Not applicable or not established from inspected methods; no masking inferred
sources

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

review Scope
selected-methods
paper Trust Assessment
score
1
display Crosses
1
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
false
peer Reviewed
true
blinding
not-applicable
masking Roles
Not applicable or not established from inspected methods; no masking inferred
basis
systematic-review-meta-analysis
sources

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
citations By Collection
vision
Not recorded
topics
  1. key
    vision:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    vision
    trust Score
    2
  2. key
    vision:emdr-youth
    title
    EMDR for youth
    collection
    vision
    trust Score
    2
journal Key
frontiersinpsychology
journal Label
Frontiers in psychology
chapter Entries
  1. id
    vision-universal-mind-mobile-lab-youth-pmid-29066991
    aliases
    None recorded
    title
    Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
    authors
    Moreno-Alcázar A, Treen D, Valiente-Gómez A, Sio-Eroles A, Pérez V, Amann BL, Radua J.
    year
    2017
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2017.01750
    pmid
    29066991
    urls

    https://doi.org/10.3389/fpsyg.2017.01750 · https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    collections

    vision

    categories

    Methods & context

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · ptsd · trauma · depression

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        findings
        text
        EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
        matched Text
        anxiety
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      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      ptsd
      evidence
      1. field
        title
        text
        Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
        matched Text
        Post-traumatic Stress
      2. field
        findings
        text
        EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
        matched Text
        PTSD
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    3. id
      trauma
      evidence
      1. field
        title
        text
        Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
        matched Text
        Post-traumatic
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    4. id
      depression
      evidence
      1. field
        findings
        text
        EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
        matched Text
        depression
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
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    age Population
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    reported Ages
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    youth Scope
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    youth Source Note
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    age Fit
    mixed-overlap
    source URL
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    basis Type
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    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
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    Review
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    Systematic review / meta-analysis
    origin
    approved-youth-20261102
    priority
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    quotes
    None recorded
    finding
    EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
    summary
    EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
    limitation
    Small older evidence base, variable bias and populations, and substantial overlap with later reviews; not an additional set of independent trials.
    evidence
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    intervention
    EMDR versus waiting, usual care, active listening or CBT; searches through January 2017.
    provider
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    See design/intervention description; otherwise unknown
    sample
    Eight RCTs, 295 participants.
    population
    age
    Predominantly children/adolescents; one young-women study had mean age 20.9.
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    mixed-overlap
    sample
    Eight RCTs, 295 participants.
    setting
    Not separately established; see population/intervention description
    community
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    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    publication-29066991
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
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    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
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    jadad Score
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    masking Roles
    Not applicable or not established from inspected methods; no masking inferred
    harms And Attrition
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    source Access
    scope
    selected-methods
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    systematic-review-meta-analysis
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    Not applicable or not established from inspected methods; no masking inferred
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    https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    review Scope
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    1
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    status
    assessed
    rating Scale
    library-trust-factor/1-3
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    false
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    blinding
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    masking Roles
    Not applicable or not established from inspected methods; no masking inferred
    basis
    systematic-review-meta-analysis
    sources

    https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    assessed At
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    review Scope
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    false
    review Limit
    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
    status
    not-applicable
    score
    Not recorded
    citation Count
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
    source Revision
    r1-7bcc23cafcaf
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    retrieved At
    2026-11-02
    study Family Id
    publication-29066991
    randomized Study Unit Id
    Not recorded
    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    EMDR

    lab Relevance
    relationship
    inspired-by
    implication
    Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    29066991
    checked At
    2026-11-02T01:32:40.558430+00:00
    pub Types

    review-article · Review · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    EMDR

    record Id
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    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-29066991
    title
    Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
    authors
    Moreno-Alcázar A, Treen D, Valiente-Gómez A, Sio-Eroles A, Pérez V, Amann BL, Radua J.
    year
    2017
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2017.01750
    pmid
    29066991
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    None recorded
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    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    EMDR

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    review-article · Review · Journal Article

    study Family Id
    publication-29066991
    randomized Study Unit Id
    Not recorded
    existing Repository Matches
    None recorded
    population
    age
    Predominantly children/adolescents; one young-women study had mean age 20.9.
    age Fit
    mixed-overlap
    sample
    Eight RCTs, 295 participants.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    EMDR versus waiting, usual care, active listening or CBT; searches through January 2017.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    systematic-review-meta-analysis
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    randomization Methods Inspected
    false
    masking
    Not applicable or not established from inspected methods; no masking inferred
    double Blinding Verified
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    proposed Crosses
    1
    approved Crosses
    Not recorded
    findings
    EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
    limitations
    Small older evidence base, variable bias and populations, and substantial overlap with later reviews; not an additional set of independent trials.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    inspired-by
    implication
    Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims.
    transfer Limit
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    source Access
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    checked At
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    pub Types

    review-article · Review · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
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    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
    review
    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
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    selected Corpus References
    None recorded
    reference Scope
    Explicit publisher reference identifiers; citation is not proof of inclusion in a meta-analysis.
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    8
    topic Id
    universal-mind-mobile-lab
    topic Title
    Universal Mind Mobile Lab · Direct response and inspired by
    trust Score
    2
  2. id
    vision-emdr-youth-youth-pmid-29066991
    aliases
    None recorded
    title
    Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
    authors
    Moreno-Alcázar A, Treen D, Valiente-Gómez A, Sio-Eroles A, Pérez V, Amann BL, Radua J.
    year
    2017
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2017.01750
    pmid
    29066991
    urls

    https://doi.org/10.3389/fpsyg.2017.01750 · https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    collections

    vision

    categories

    Methods & context

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · ptsd · trauma · depression

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        findings
        text
        EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
        matched Text
        anxiety
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      ptsd
      evidence
      1. field
        title
        text
        Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
        matched Text
        Post-traumatic Stress
      2. field
        findings
        text
        EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
        matched Text
        PTSD
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    3. id
      trauma
      evidence
      1. field
        title
        text
        Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
        matched Text
        Post-traumatic
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    4. id
      depression
      evidence
      1. field
        findings
        text
        EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
        matched Text
        depression
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    age Groups

    children · adolescents · youth · adults

    age Population
    record Id
    youth-pmid-29066991
    collections

    vision

    groups

    children · adolescents · youth · adults

    reported Ages
    Predominantly children/adolescents; one young-women study had mean age 20.9.
    youth Scope
    included
    youth Source Note
    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
    mixed-overlap
    source URL
    https://pubmed.ncbi.nlm.nih.gov/29066991/
    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
    None recorded
    kind
    Review
    design
    Systematic review / meta-analysis
    origin
    approved-youth-20261102
    priority
    1
    quotes
    None recorded
    finding
    EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
    summary
    EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
    limitation
    Small older evidence base, variable bias and populations, and substantial overlap with later reviews; not an additional set of independent trials.
    evidence
    evidence Type
    Systematic review / meta-analysis
    intervention
    EMDR versus waiting, usual care, active listening or CBT; searches through January 2017.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    sample
    Eight RCTs, 295 participants.
    population
    age
    Predominantly children/adolescents; one young-women study had mean age 20.9.
    age Fit
    mixed-overlap
    sample
    Eight RCTs, 295 participants.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    publication-29066991
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    masking Roles
    Not applicable or not established from inspected methods; no masking inferred
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    retrieved At
    2026-11-02
    study Design Assessment
    category
    review
    is Randomized Controlled Trial
    false
    peer Reviewed
    true
    basis
    systematic-review-meta-analysis
    masking Roles
    Not applicable or not established from inspected methods; no masking inferred
    sources

    https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    review Scope
    selected-methods
    paper Trust Assessment
    score
    1
    display Crosses
    1
    scope
    Paper
    status
    assessed
    rating Scale
    library-trust-factor/1-3
    randomized Controlled Trial
    false
    peer Reviewed
    true
    blinding
    not-applicable
    masking Roles
    Not applicable or not established from inspected methods; no masking inferred
    basis
    systematic-review-meta-analysis
    sources

    https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    assessed At
    2026-11-02
    review Scope
    selected-methods
    human Approval
    false
    review Limit
    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
    status
    not-applicable
    score
    Not recorded
    citation Count
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
    source Revision
    r1-7bcc23cafcaf
    source Content Hash
    7bcc23cafcaf6ede3ea39f1b291468e2e0e6b85330112f4537d4b40573d781a8
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

    retrieved At
    2026-11-02
    study Family Id
    publication-29066991
    randomized Study Unit Id
    Not recorded
    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    EMDR

    lab Relevance
    relationship
    inspired-by
    implication
    Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    29066991
    checked At
    2026-11-02T01:32:40.558430+00:00
    pub Types

    review-article · Review · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    EMDR

    record Id
    youth-pmid-29066991
    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-29066991
    title
    Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
    authors
    Moreno-Alcázar A, Treen D, Valiente-Gómez A, Sio-Eroles A, Pérez V, Amann BL, Radua J.
    year
    2017
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2017.01750
    pmid
    29066991
    pmcid
    PMC5641384
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    EMDR

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    review-article · Review · Journal Article

    study Family Id
    publication-29066991
    randomized Study Unit Id
    Not recorded
    existing Repository Matches
    None recorded
    population
    age
    Predominantly children/adolescents; one young-women study had mean age 20.9.
    age Fit
    mixed-overlap
    sample
    Eight RCTs, 295 participants.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    EMDR versus waiting, usual care, active listening or CBT; searches through January 2017.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    systematic-review-meta-analysis
    category
    review
    randomization Methods Inspected
    false
    masking
    Not applicable or not established from inspected methods; no masking inferred
    double Blinding Verified
    false
    proposed Crosses
    1
    approved Crosses
    Not recorded
    findings
    EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
    limitations
    Small older evidence base, variable bias and populations, and substantial overlap with later reviews; not an additional set of independent trials.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    inspired-by
    implication
    Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
    1. type
      primary bibliographic record
      url
      https://pubmed.ncbi.nlm.nih.gov/29066991/
      retrieved At
      2026-11-02
      sha256
      79fed09c9196dcd4d76ab0109506d6f4f7d009a4e73997ea10babf8f395883cc
      hash Scope
      normalized Europe PMC core metadata snapshot
    2. type
      publisher DOI
      url
      https://doi.org/10.3389/fpsyg.2017.01750
      retrieved At
      2026-11-02
    3. type
      PMC article
      url
      https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/
      retrieved At
      2026-11-02
      access
      Full text cached
    4. type
      full-text-xml
      url
      https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML
      retrieved At
      2026-11-02T00:58:31.200409+00:00
      sha256
      d579f50b5c7cfb4bec7a0a21a36bb799acb134089c7212921af6ea54bb42e4b9
    5. type
      DOI-metadata
      url
      https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750
      retrieved At
      2026-11-02T00:58:31.202735+00:00
      sha256
      fc4b49c6066dbb135f45f13fe1b4da73d840cb8d9b54712a306402133b098bc7
    publication Status
    pmid
    29066991
    checked At
    2026-11-02T01:32:40.558430+00:00
    pub Types

    review-article · Review · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
    review
    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
    false
    selected Corpus References
    None recorded
    reference Scope
    Explicit publisher reference identifiers; citation is not proof of inclusion in a meta-analysis.
    content Hash
    7bcc23cafcaf6ede3ea39f1b291468e2e0e6b85330112f4537d4b40573d781a8
    revision
    r1-7bcc23cafcaf
    archive Entries
    None recorded
    collection
    vision
    chapter Number
    8
    topic Id
    emdr-youth
    topic Title
    EMDR for youth
    trust Score
    2
evidence
evidence Type
Systematic review / meta-analysis
intervention
EMDR versus waiting, usual care, active listening or CBT; searches through January 2017.
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
Eight RCTs, 295 participants.
population
age
Predominantly children/adolescents; one young-women study had mean age 20.9.
age Fit
mixed-overlap
sample
Eight RCTs, 295 participants.
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-29066991
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Provides historical context for clinical EMDR access; prioritise newer syntheses for current claims. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Not applicable or not established from inspected methods; no masking inferred
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/29066991/ · https://doi.org/10.3389/fpsyg.2017.01750 · https://pmc.ncbi.nlm.nih.gov/articles/PMC5641384/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5641384/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2017.01750

retrieved At
2026-11-02
jadad
status
not-applicable
score
Not recorded
condition Evidence
  1. id
    anxiety
    evidence
    1. field
      findings
      text
      EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
      matched Text
      anxiety
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
  2. id
    ptsd
    evidence
    1. field
      title
      text
      Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
      matched Text
      Post-traumatic Stress
    2. field
      findings
      text
      EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
      matched Text
      PTSD
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
  3. id
    trauma
    evidence
    1. field
      title
      text
      Efficacy of Eye Movement Desensitization and Reprocessing in Children and Adolescent with Post-traumatic Stress Disorder: A Meta-Analysis of Randomized Controlled Trials.
      matched Text
      Post-traumatic
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
  4. id
    depression
    evidence
    1. field
      findings
      text
      EMDR reduced PTSD and anxiety relative to inactive comparators; the depression result was not statistically significant. Comparisons with CBT did not establish a clear advantage.
      matched Text
      depression
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
conditions

anxiety · ptsd · trauma · depression

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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