Universal Informatics · Research reading room

A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.

Ritvo P, Ahmad F, El Morr C, Pirbaglou M, Moineddin R, MVC Team. · JMIR mental health · 2021 · Randomized controlled trial report · double blinding not verified

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.

Recorded limitations

Disrupted campus context, inactive comparator; reports a different intervention cycle but shares registry with earlier publication. Conservatively grouped as one programme family pending participant-overlap audit.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial report · double blinding not verified
assessment
category
rct-masking-unclear
is Randomized Controlled Trial
true
peer Reviewed
true
basis
Randomised controlled trial during university strike
masking Roles
Off-site computer blocks and opaque envelopes; sustained masking not established.
sources

https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

review Scope
selected-methods
trust Factor
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
masking Roles
Off-site computer blocks and opaque envelopes; sustained masking not established.
basis
Randomised controlled trial during university strike
sources

https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial report · double blinding not verified
intervention
Eight-week guided mindfulness/CBT virtual community versus waitlist
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
154 randomised
population
age
18+; mean 23.1
age Fit
mixed-overlap
sample
154 randomised
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
mindfulness-virtual-community-programme
trial Registries

ISRCTN92827275

registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Digital programmes can have context-dependent results; measure performance locally rather than assuming earlier results transfer. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Off-site computer blocks and opaque envelopes; sustained masking not established.
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

retrieved At
2026-11-02
Topics and recorded topic scores
  1. key
    language:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    language
    trust Score
    3
  2. key
    language:mindfulness-youth
    title
    Mindfulness for youth
    collection
    language
    trust Score
    2
Citation snapshot and identifiers
id
youth-pmid-33264098
doi
10.2196/23491
pmid
33264098
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
language
Not recorded
Complete approved library record
lab Relevance
relationship
limits
implication
Digital programmes can have context-dependent results; measure performance locally rather than assuming earlier results transfer.
transfer Limit
Component evidence does not establish efficacy of the combined Universal Mind lab model.
institutions
None recorded
institution Evidence
None recorded
research Topics

Mindfulness

publication Status
pmid
33264098
checked At
2026-11-02T01:32:43.603683+00:00
pub Types

research-article · Journal Article

indexed Notices
  1. source
    MED
    id
    33493128
    reference
    JMIR Ment Health. 2021 Jan 25;8(1):e27160. doi: 10.2196/27160
    type
    Erratum in
    order In
    1
crossref Updates
None recorded
notice Records
  1. pmid
    33493128
    type
    Erratum in
    title
    Correction: A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
    doi
    10.2196/27160
    pmcid
    PMC7870347
    url
    https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID%3A33493128+AND+SRC%3AMED&format=json&resultType=core
    sha256
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    retrieved At
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    fulltext URL
    https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7870347/fullTextXML
    fulltext SHA256
    0403ff6a85ec96c6786a1964b470886180a042245ea0d7faf5590114a23633a3
scope
Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
notice Summary
2021 correction removes an incorrect group-author equal-contribution footnote; no outcome correction in the notice.
randomized Study Unit Id
mindfulness-virtual-community-programme
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-02
assessment
AI assessed; human approved for publication
scope
Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
source Revision
r1-d4170c66f2d7
source Content Hash
d4170c66f2d70a3e8030546daf0845e33c410388d8a46385ae0576f688c528ca
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

retrieved At
2026-11-02
study Family Id
mindfulness-virtual-community-programme
approaches

Mindfulness

id
youth-pmid-33264098
aliases
None recorded
title
A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
journal
JMIR mental health
neurotransmitters
None recorded
year
2021
authors
Ritvo P, Ahmad F, El Morr C, Pirbaglou M, Moineddin R, MVC Team.
design
Randomized controlled trial report · double blinding not verified
kind
Journal article
identity Conflict
Not recorded
doi
10.2196/23491
pmid
33264098
urls

https://doi.org/10.2196/23491 · https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
limitation
Disrupted campus context, inactive comparator; reports a different intervention cycle but shares registry with earlier publication. Conservatively grouped as one programme family pending participant-overlap audit.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
rct-masking-unclear
is Randomized Controlled Trial
true
peer Reviewed
true
basis
Randomised controlled trial during university strike
masking Roles
Off-site computer blocks and opaque envelopes; sustained masking not established.
sources

https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

review Scope
selected-methods
paper Trust Assessment
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
not-confirmed
masking Roles
Off-site computer blocks and opaque envelopes; sustained masking not established.
basis
Randomised controlled trial during university strike
sources

https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
citations By Collection
language
Not recorded
topics
  1. key
    language:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    language
    trust Score
    3
  2. key
    language:mindfulness-youth
    title
    Mindfulness for youth
    collection
    language
    trust Score
    2
journal Key
jmirmentalhealth
journal Label
JMIR mental health
chapter Entries
  1. id
    language-universal-mind-mobile-lab-youth-pmid-33264098
    aliases
    None recorded
    title
    A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
    authors
    Ritvo P, Ahmad F, El Morr C, Pirbaglou M, Moineddin R, MVC Team.
    year
    2021
    journal
    JMIR mental health
    doi
    10.2196/23491
    pmid
    33264098
    urls

    https://doi.org/10.2196/23491 · https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

    collections

    language

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · depression · stress

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        title
        text
        A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
        matched Text
        Anxiety
      2. field
        findings
        text
        Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
        matched Text
        anxiety
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      depression
      evidence
      1. field
        title
        text
        A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
        matched Text
        Depression
      2. field
        findings
        text
        Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
        matched Text
        depression
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    3. id
      stress
      evidence
      1. field
        title
        text
        A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
        matched Text
        Stress
      2. field
        findings
        text
        Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
        matched Text
        stress
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    age Groups

    youth · adults

    age Population
    record Id
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    collections

    language

    groups

    youth · adults

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    18+; mean 23.1
    youth Scope
    included
    youth Source Note
    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
    mixed-overlap
    source URL
    https://pubmed.ncbi.nlm.nih.gov/33264098/
    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
    None recorded
    kind
    Journal article
    design
    Randomized controlled trial report · double blinding not verified
    origin
    approved-youth-20261102
    priority
    1
    quotes
    None recorded
    finding
    Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
    summary
    Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
    limitation
    Disrupted campus context, inactive comparator; reports a different intervention cycle but shares registry with earlier publication. Conservatively grouped as one programme family pending participant-overlap audit.
    evidence
    evidence Type
    Randomized controlled trial report · double blinding not verified
    intervention
    Eight-week guided mindfulness/CBT virtual community versus waitlist
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    sample
    154 randomised
    population
    age
    18+; mean 23.1
    age Fit
    mixed-overlap
    sample
    154 randomised
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    mindfulness-virtual-community-programme
    trial Registries

    ISRCTN92827275

    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Digital programmes can have context-dependent results; measure performance locally rather than assuming earlier results transfer. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    masking Roles
    Off-site computer blocks and opaque envelopes; sustained masking not established.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    source Access
    scope
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    source URLs

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    retrieved At
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    category
    rct-masking-unclear
    is Randomized Controlled Trial
    true
    peer Reviewed
    true
    basis
    Randomised controlled trial during university strike
    masking Roles
    Off-site computer blocks and opaque envelopes; sustained masking not established.
    sources

    https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

    review Scope
    selected-methods
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    Paper
    status
    assessed
    rating Scale
    library-trust-factor/1-3
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    not-confirmed
    masking Roles
    Off-site computer blocks and opaque envelopes; sustained masking not established.
    basis
    Randomised controlled trial during university strike
    sources

    https://pubmed.ncbi.nlm.nih.gov/33264098/ · https://doi.org/10.2196/23491 · https://pmc.ncbi.nlm.nih.gov/articles/PMC7833974/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC7833974/fullTextXML · https://api.crossref.org/works/10.2196%2F23491

    assessed At
    2026-11-02
    review Scope
    selected-methods
    human Approval
    false
    review Limit
    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
    status
    unassessed
    score
    Not recorded
    citation Count
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
    source Revision
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    retrieved At
    2026-11-02
    study Family Id
    mindfulness-virtual-community-programme
    randomized Study Unit Id
    mindfulness-virtual-community-programme
    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    Mindfulness

    lab Relevance
    relationship
    limits
    implication
    Digital programmes can have context-dependent results; measure performance locally rather than assuming earlier results transfer.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
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    checked At
    2026-11-02T01:32:43.603683+00:00
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    indexed Notices
    1. source
      MED
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      reference
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      type
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    crossref Updates
    None recorded
    notice Records
    1. pmid
      33493128
      type
      Erratum in
      title
      Correction: A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
      doi
      10.2196/27160
      pmcid
      PMC7870347
      url
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    notice Summary
    2021 correction removes an incorrect group-author equal-contribution footnote; no outcome correction in the notice.
    approaches

    Mindfulness

    record Id
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    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-33264098
    title
    A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
    authors
    Ritvo P, Ahmad F, El Morr C, Pirbaglou M, Moineddin R, MVC Team.
    year
    2021
    journal
    JMIR mental health
    doi
    10.2196/23491
    pmid
    33264098
    pmcid
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    trial Registries

    ISRCTN92827275

    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    Mindfulness

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    research-article · Journal Article

    study Family Id
    mindfulness-virtual-community-programme
    randomized Study Unit Id
    mindfulness-virtual-community-programme
    existing Repository Matches
    None recorded
    population
    age
    18+; mean 23.1
    age Fit
    mixed-overlap
    sample
    154 randomised
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Eight-week guided mindfulness/CBT virtual community versus waitlist
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    Randomised controlled trial during university strike
    category
    randomized-report
    randomization Methods Inspected
    true
    masking
    Off-site computer blocks and opaque envelopes; sustained masking not established.
    double Blinding Verified
    false
    proposed Crosses
    2
    approved Crosses
    Not recorded
    findings
    Perceived stress improved (ITT β −2.31, p=.03); depression, anxiety and mindfulness did not differ significantly.
    limitations
    Disrupted campus context, inactive comparator; reports a different intervention cycle but shares registry with earlier publication. Conservatively grouped as one programme family pending participant-overlap audit.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    limits
    implication
    Digital programmes can have context-dependent results; measure performance locally rather than assuming earlier results transfer.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
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    pub Types

    research-article · Journal Article

    indexed Notices
    1. source
      MED
      id
      33493128
      reference
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  2. id
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    title
    A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
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    Ritvo P, Ahmad F, El Morr C, Pirbaglou M, Moineddin R, MVC Team.
    year
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    doi
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    collections

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    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

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    condition Evidence
    1. id
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      1. field
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        text
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        matched Text
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        text
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        matched Text
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        matched Text
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    relationship Note
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    pathways
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    formal Risk Of Bias Tool Applied
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    citation Snapshot
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    A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
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    institution Evidence
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    publication Type

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    study Family Id
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evidence
evidence Type
Randomized controlled trial report · double blinding not verified
intervention
Eight-week guided mindfulness/CBT virtual community versus waitlist
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
154 randomised
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age
18+; mean 23.1
age Fit
mixed-overlap
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154 randomised
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Not separately established; see population/intervention description
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Not assigned
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Specific outcomes are reported in the finding and retained appraisal.
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trial Registries

ISRCTN92827275

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Identifiers explicitly reported in article abstract; other registrations remain unverified
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Digital programmes can have context-dependent results; measure performance locally rather than assuming earlier results transfer. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Off-site computer blocks and opaque envelopes; sustained masking not established.
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
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true
methods Inspected
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full Text Appraisal Claim
false
level
selected-methods
source URLs

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retrieved At
2026-11-02
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
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    evidence
    1. field
      title
      text
      A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
      matched Text
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    2. field
      findings
      text
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      matched Text
      anxiety
    scope
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  2. id
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    1. field
      title
      text
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      matched Text
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      findings
      text
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      matched Text
      depression
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  3. id
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    1. field
      title
      text
      A Mindfulness-Based Intervention for Student Depression, Anxiety, and Stress: Randomized Controlled Trial.
      matched Text
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      text
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      matched Text
      stress
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conditions

anxiety · depression · stress

topic Trust Scores

3 · 2

full Text
status
not-indexed
retrieval Available
false

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