Universal Informatics · Research reading room

Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.

Sibinga EMS, Webb L, Perin J, Tepper V, Kerrigan D, Grieb S, Denison J, Ellen J. · AIDS care · 2022 · Randomized controlled trial report · single masked role verified

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

Medication adherence improved post-programme; viral-load comparison p=.052 does not meet conventional .05 threshold. Mindfulness later decreased.

Recorded limitations

Small sample, baseline viral-load/mindfulness imbalance and pooled control conditions; medically specific HIV cohort.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial report · single masked role verified
assessment
category
single-blind-rct
is Randomized Controlled Trial
true
peer Reviewed
true
basis
Randomised controlled trial
masking Roles
Outcome/data extraction staff masked; participant/provider masking not established.
sources

https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

review Scope
selected-methods
trust Factor
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
single
masking Roles
Outcome/data extraction staff masked; participant/provider masking not established.
basis
Randomised controlled trial
sources

https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial report · single masked role verified
intervention
Nine adapted MBSR sessions versus health-education/usual-care controls
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
74 randomised (34 MBSR, 32 health education, 8 usual care); 68 retained after withdrawals
population
age
13–24; mean 20.5
age Fit
mixed-overlap
sample
74 randomised (34 MBSR, 32 health education, 8 usual care); 68 retained after withdrawals
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
hiv-youth-mbsr-2015-2017
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Outcome/data extraction staff masked; participant/provider masking not established.
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

retrieved At
2026-11-02
Topics and recorded topic scores
  1. key
    language:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    language
    trust Score
    3
  2. key
    language:mindfulness-youth
    title
    Mindfulness for youth
    collection
    language
    trust Score
    2
Citation snapshot and identifiers
id
youth-pmid-35914112
doi
10.1080/09540121.2022.2105796
pmid
35914112
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
language
Not recorded
Complete approved library record
lab Relevance
relationship
inspired-by
implication
Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab.
transfer Limit
Component evidence does not establish efficacy of the combined Universal Mind lab model.
institutions
None recorded
institution Evidence
None recorded
research Topics

Mindfulness

publication Status
pmid
35914112
checked At
2026-11-02T01:32:46.748043+00:00
pub Types

research-article · Randomized Controlled Trial · Journal Article · Research Support, N.I.H., Extramural

indexed Notices
None recorded
crossref Updates
None recorded
notice Records
None recorded
scope
Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
notice Summary
Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
randomized Study Unit Id
hiv-youth-mbsr-2015-2017
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-02
assessment
AI assessed; human approved for publication
scope
Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
source Revision
r1-66fecc774b21
source Content Hash
66fecc774b21dbad9bdbdcfa04307ab6916ca610582820b88ea57085c6417633
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

retrieved At
2026-11-02
study Family Id
hiv-youth-mbsr-2015-2017
approaches

Mindfulness

id
youth-pmid-35914112
aliases
None recorded
title
Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.
journal
AIDS care
neurotransmitters
None recorded
year
2022
authors
Sibinga EMS, Webb L, Perin J, Tepper V, Kerrigan D, Grieb S, Denison J, Ellen J.
design
Randomized controlled trial report · single masked role verified
kind
Journal article
identity Conflict
Not recorded
doi
10.1080/09540121.2022.2105796
pmid
35914112
urls

https://doi.org/10.1080/09540121.2022.2105796 · https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Medication adherence improved post-programme; viral-load comparison p=.052 does not meet conventional .05 threshold. Mindfulness later decreased.
limitation
Small sample, baseline viral-load/mindfulness imbalance and pooled control conditions; medically specific HIV cohort.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
single-blind-rct
is Randomized Controlled Trial
true
peer Reviewed
true
basis
Randomised controlled trial
masking Roles
Outcome/data extraction staff masked; participant/provider masking not established.
sources

https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

review Scope
selected-methods
paper Trust Assessment
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
single
masking Roles
Outcome/data extraction staff masked; participant/provider masking not established.
basis
Randomised controlled trial
sources

https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
citations By Collection
language
Not recorded
topics
  1. key
    language:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    language
    trust Score
    3
  2. key
    language:mindfulness-youth
    title
    Mindfulness for youth
    collection
    language
    trust Score
    2
journal Key
aidscare
journal Label
AIDS care
chapter Entries
  1. id
    language-universal-mind-mobile-lab-youth-pmid-35914112
    aliases
    None recorded
    title
    Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.
    authors
    Sibinga EMS, Webb L, Perin J, Tepper V, Kerrigan D, Grieb S, Denison J, Ellen J.
    year
    2022
    journal
    AIDS care
    doi
    10.1080/09540121.2022.2105796
    pmid
    35914112
    urls

    https://doi.org/10.1080/09540121.2022.2105796 · https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

    collections

    language

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions
    None recorded
    condition Evidence
    None recorded
    age Groups

    adolescents · youth · adults

    age Population
    record Id
    youth-pmid-35914112
    collections

    language

    groups

    adolescents · youth · adults

    reported Ages
    13–24; mean 20.5
    youth Scope
    included
    youth Source Note
    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
    mixed-overlap
    source URL
    https://pubmed.ncbi.nlm.nih.gov/35914112/
    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
    None recorded
    kind
    Journal article
    design
    Randomized controlled trial report · single masked role verified
    origin
    approved-youth-20261102
    priority
    1
    quotes
    None recorded
    finding
    Medication adherence improved post-programme; viral-load comparison p=.052 does not meet conventional .05 threshold. Mindfulness later decreased.
    summary
    Medication adherence improved post-programme; viral-load comparison p=.052 does not meet conventional .05 threshold. Mindfulness later decreased.
    limitation
    Small sample, baseline viral-load/mindfulness imbalance and pooled control conditions; medically specific HIV cohort.
    evidence
    evidence Type
    Randomized controlled trial report · single masked role verified
    intervention
    Nine adapted MBSR sessions versus health-education/usual-care controls
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    sample
    74 randomised (34 MBSR, 32 health education, 8 usual care); 68 retained after withdrawals
    population
    age
    13–24; mean 20.5
    age Fit
    mixed-overlap
    sample
    74 randomised (34 MBSR, 32 health education, 8 usual care); 68 retained after withdrawals
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    hiv-youth-mbsr-2015-2017
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    masking Roles
    Outcome/data extraction staff masked; participant/provider masking not established.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    source Access
    scope
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    true
    methods Inspected
    true
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    retrieved At
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    single-blind-rct
    is Randomized Controlled Trial
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    Outcome/data extraction staff masked; participant/provider masking not established.
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    https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

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    https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://doi.org/10.1080/09540121.2022.2105796 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

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    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
    status
    unassessed
    score
    Not recorded
    citation Count
    Not recorded
    citation Snapshot
    count
    Not recorded
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    Not recorded
    retrieved At
    Not recorded
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    not-assessed
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    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
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    r1-66fecc774b21
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    retrieved At
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    study Family Id
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    randomized Study Unit Id
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    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    Mindfulness

    lab Relevance
    relationship
    inspired-by
    implication
    Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    35914112
    checked At
    2026-11-02T01:32:46.748043+00:00
    pub Types

    research-article · Randomized Controlled Trial · Journal Article · Research Support, N.I.H., Extramural

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    Mindfulness

    record Id
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    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-35914112
    title
    Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.
    authors
    Sibinga EMS, Webb L, Perin J, Tepper V, Kerrigan D, Grieb S, Denison J, Ellen J.
    year
    2022
    journal
    AIDS care
    doi
    10.1080/09540121.2022.2105796
    pmid
    35914112
    pmcid
    PMC9712224
    trial Registries
    None recorded
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    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    Mindfulness

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    research-article · Randomized Controlled Trial · Journal Article · Research Support, N.I.H., Extramural

    study Family Id
    hiv-youth-mbsr-2015-2017
    randomized Study Unit Id
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    None recorded
    population
    age
    13–24; mean 20.5
    age Fit
    mixed-overlap
    sample
    74 randomised (34 MBSR, 32 health education, 8 usual care); 68 retained after withdrawals
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Nine adapted MBSR sessions versus health-education/usual-care controls
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    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
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    Randomised controlled trial
    category
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    true
    masking
    Outcome/data extraction staff masked; participant/provider masking not established.
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    proposed Crosses
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    approved Crosses
    Not recorded
    findings
    Medication adherence improved post-programme; viral-load comparison p=.052 does not meet conventional .05 threshold. Mindfulness later decreased.
    limitations
    Small sample, baseline viral-load/mindfulness imbalance and pooled control conditions; medically specific HIV cohort.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    inspired-by
    implication
    Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
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    selected-methods
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    pub Types

    research-article · Randomized Controlled Trial · Journal Article · Research Support, N.I.H., Extramural

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
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    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
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    jadad Score
    Not recorded
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    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
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    status
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    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
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    selected Corpus References

    youth-pmid-29067834

    reference Scope
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    collection
    language
    chapter Number
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    topic Id
    universal-mind-mobile-lab
    topic Title
    Universal Mind Mobile Lab · Direct response and inspired by
    trust Score
    3
  2. id
    language-mindfulness-youth-youth-pmid-35914112
    aliases
    None recorded
    title
    Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.
    authors
    Sibinga EMS, Webb L, Perin J, Tepper V, Kerrigan D, Grieb S, Denison J, Ellen J.
    year
    2022
    journal
    AIDS care
    doi
    10.1080/09540121.2022.2105796
    pmid
    35914112
    urls

    https://doi.org/10.1080/09540121.2022.2105796 · https://pubmed.ncbi.nlm.nih.gov/35914112/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC9712224/ · https://api.crossref.org/works/10.1080%2F09540121.2022.2105796 · https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pmc&id=9712224&retmode=xml

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    conditions
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    condition Evidence
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    relationship Note
    Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab. Component evidence does not establish efficacy of the combined Universal Mind lab model.
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    pathways
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    formal Risk Of Bias Tool Applied
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    citation Snapshot
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    institution Evidence
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    research Topics

    Mindfulness

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    inspired-by
    implication
    Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab.
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    indexed Notices
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    crossref Updates
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    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    Mindfulness

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    id
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    title
    Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.
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    Sibinga EMS, Webb L, Perin J, Tepper V, Kerrigan D, Grieb S, Denison J, Ellen J.
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    AIDS care
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    10.1080/09540121.2022.2105796
    pmid
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    None recorded
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    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    Mindfulness

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    research-article · Randomized Controlled Trial · Journal Article · Research Support, N.I.H., Extramural

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    Medication adherence improved post-programme; viral-load comparison p=.052 does not meet conventional .05 threshold. Mindfulness later decreased.
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    Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab.
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    indexed Notices
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    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
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mixed-overlap
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74 randomised (34 MBSR, 32 health education, 8 usual care); 68 retained after withdrawals
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Specific outcomes are reported in the finding and retained appraisal.
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hiv-youth-mbsr-2015-2017
trial Registries
None recorded
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Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Shows why supportive skills should complement clinical care; cannot generalise disease outcomes to the lab. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
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harms And Attrition
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source Access
scope
selected-methods
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3 · 2

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