Universal Informatics · Research reading room

Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.

Azimisefat P, de Jongh A, Rajabi S, Kanske P, Jamshidi F. · Frontiers in psychology · 2022 · Randomized controlled trial report · single masked role verified

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.

Recorded limitations

Small female-only sample, short follow-up, self-report outcomes and no active attention control.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial report · single masked role verified
assessment
category
single-blind-rct
is Randomized Controlled Trial
true
peer Reviewed
true
basis
rct
masking Roles
participants
Unblinded
providers
Unblinded
assessors
Masked
analysts
Masked
sources

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

review Scope
selected-methods
trust Factor
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
single
masking Roles
participants
Unblinded
providers
Unblinded
assessors
Masked
analysts
Masked
basis
rct
sources

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial report · single masked role verified
intervention
Six sessions of EMDR or virtual-reality exposure versus waiting; one-week post-treatment assessment.
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
45 randomized, 15 per arm.
population
age
Female adolescents screened at 16–18; arm means around 17.
age Fit
target-range
sample
45 randomized, 15 per arm.
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-36186313
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
participants
Unblinded
providers
Unblinded
assessors
Masked
analysts
Masked
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

retrieved At
2026-11-02
Topics and recorded topic scores
  1. key
    vision:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    vision
    trust Score
    2
  2. key
    vision:emdr-youth
    title
    EMDR for youth
    collection
    vision
    trust Score
    2
Citation snapshot and identifiers
id
youth-pmid-36186313
doi
10.3389/fpsyg.2022.919148
pmid
36186313
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
vision
Not recorded
Complete approved library record
lab Relevance
relationship
inspired-by
implication
Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment.
transfer Limit
Component evidence does not establish efficacy of the combined Universal Mind lab model.
institutions
None recorded
institution Evidence
None recorded
research Topics

EMDR

publication Status
pmid
36186313
checked At
2026-11-02T01:32:46.748943+00:00
pub Types

research-article · Journal Article

indexed Notices
None recorded
crossref Updates
None recorded
notice Records
None recorded
scope
Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
notice Summary
Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
randomized Study Unit Id
publication-36186313
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-02
assessment
AI assessed; human approved for publication
scope
Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
source Revision
r1-ce11015457b2
source Content Hash
ce11015457b240cd0f98b3ee78c6ddc913fd846aaf0c8ef9a04128c44c108575
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

retrieved At
2026-11-02
study Family Id
publication-36186313
approaches

EMDR

id
youth-pmid-36186313
aliases
None recorded
title
Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
journal
Frontiers in psychology
neurotransmitters
None recorded
year
2022
authors
Azimisefat P, de Jongh A, Rajabi S, Kanske P, Jamshidi F.
design
Randomized controlled trial report · single masked role verified
kind
Journal article
identity Conflict
Not recorded
doi
10.3389/fpsyg.2022.919148
pmid
36186313
urls

https://doi.org/10.3389/fpsyg.2022.919148 · https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

collections

vision

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
limitation
Small female-only sample, short follow-up, self-report outcomes and no active attention control.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
single-blind-rct
is Randomized Controlled Trial
true
peer Reviewed
true
basis
rct
masking Roles
participants
Unblinded
providers
Unblinded
assessors
Masked
analysts
Masked
sources

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

review Scope
selected-methods
paper Trust Assessment
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
single
masking Roles
participants
Unblinded
providers
Unblinded
assessors
Masked
analysts
Masked
basis
rct
sources

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
citations By Collection
vision
Not recorded
topics
  1. key
    vision:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    vision
    trust Score
    2
  2. key
    vision:emdr-youth
    title
    EMDR for youth
    collection
    vision
    trust Score
    2
journal Key
frontiersinpsychology
journal Label
Frontiers in psychology
chapter Entries
  1. id
    vision-universal-mind-mobile-lab-youth-pmid-36186313
    aliases
    None recorded
    title
    Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
    authors
    Azimisefat P, de Jongh A, Rajabi S, Kanske P, Jamshidi F.
    year
    2022
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2022.919148
    pmid
    36186313
    urls

    https://doi.org/10.3389/fpsyg.2022.919148 · https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

    collections

    vision

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · stress

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        title
        text
        Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
        matched Text
        anxiety
      2. field
        findings
        text
        Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
        matched Text
        anxiety
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      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      stress
      evidence
      1. field
        findings
        text
        Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
        matched Text
        stress
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    age Groups

    adolescents · youth

    age Population
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    vision

    groups

    adolescents · youth

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    Female adolescents screened at 16–18; arm means around 17.
    youth Scope
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    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
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    source URL
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    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
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    Journal article
    design
    Randomized controlled trial report · single masked role verified
    origin
    approved-youth-20261102
    priority
    1
    quotes
    None recorded
    finding
    Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
    summary
    Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
    limitation
    Small female-only sample, short follow-up, self-report outcomes and no active attention control.
    evidence
    evidence Type
    Randomized controlled trial report · single masked role verified
    intervention
    Six sessions of EMDR or virtual-reality exposure versus waiting; one-week post-treatment assessment.
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    age
    Female adolescents screened at 16–18; arm means around 17.
    age Fit
    target-range
    sample
    45 randomized, 15 per arm.
    setting
    Not separately established; see population/intervention description
    community
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    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    publication-36186313
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
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    jadad Score
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    masking Roles
    participants
    Unblinded
    providers
    Unblinded
    assessors
    Masked
    analysts
    Masked
    harms And Attrition
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    review Scope
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    assessed At
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    false
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    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
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    Not recorded
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    Not recorded
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    Not recorded
    retrieved At
    Not recorded
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    not-assessed
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    approved-for-publication
    approved By
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    retrieved At
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    study Family Id
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    randomized Study Unit Id
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    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    EMDR

    lab Relevance
    relationship
    inspired-by
    implication
    Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment.
    transfer Limit
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    indexed Notices
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    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    EMDR

    record Id
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    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-36186313
    title
    Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
    authors
    Azimisefat P, de Jongh A, Rajabi S, Kanske P, Jamshidi F.
    year
    2022
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2022.919148
    pmid
    36186313
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    None recorded
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    Identifiers explicitly reported in article abstract; other registrations remain unverified
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    topics

    EMDR

    institutions
    None recorded
    institution Evidence
    None recorded
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    research-article · Journal Article

    study Family Id
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    randomized Study Unit Id
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    Female adolescents screened at 16–18; arm means around 17.
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    sample
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    setting
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    findings
    Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
    limitations
    Small female-only sample, short follow-up, self-report outcomes and no active attention control.
    harms And Attrition
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    lab Relevance
    relationship
    inspired-by
    implication
    Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment.
    transfer Limit
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    checked At
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    pub Types

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    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
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    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
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    jadad Score
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    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
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    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
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    Universal Mind Mobile Lab · Direct response and inspired by
    trust Score
    2
  2. id
    vision-emdr-youth-youth-pmid-36186313
    aliases
    None recorded
    title
    Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
    authors
    Azimisefat P, de Jongh A, Rajabi S, Kanske P, Jamshidi F.
    year
    2022
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2022.919148
    pmid
    36186313
    urls

    https://doi.org/10.3389/fpsyg.2022.919148 · https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

    collections

    vision

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · stress

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        title
        text
        Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
        matched Text
        anxiety
      2. field
        findings
        text
        Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
        matched Text
        anxiety
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      stress
      evidence
      1. field
        findings
        text
        Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
        matched Text
        stress
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    age Groups

    adolescents · youth

    age Population
    record Id
    youth-pmid-36186313
    collections

    vision

    groups

    adolescents · youth

    reported Ages
    Female adolescents screened at 16–18; arm means around 17.
    youth Scope
    focus
    youth Source Note
    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
    target-range
    source URL
    https://pubmed.ncbi.nlm.nih.gov/36186313/
    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
    None recorded
    kind
    Journal article
    design
    Randomized controlled trial report · single masked role verified
    origin
    approved-youth-20261102
    priority
    1
    quotes
    None recorded
    finding
    Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
    summary
    Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
    limitation
    Small female-only sample, short follow-up, self-report outcomes and no active attention control.
    evidence
    evidence Type
    Randomized controlled trial report · single masked role verified
    intervention
    Six sessions of EMDR or virtual-reality exposure versus waiting; one-week post-treatment assessment.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    sample
    45 randomized, 15 per arm.
    population
    age
    Female adolescents screened at 16–18; arm means around 17.
    age Fit
    target-range
    sample
    45 randomized, 15 per arm.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    publication-36186313
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    masking Roles
    participants
    Unblinded
    providers
    Unblinded
    assessors
    Masked
    analysts
    Masked
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

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    retrieved At
    2026-11-02
    study Design Assessment
    category
    single-blind-rct
    is Randomized Controlled Trial
    true
    peer Reviewed
    true
    basis
    rct
    masking Roles
    participants
    Unblinded
    providers
    Unblinded
    assessors
    Masked
    analysts
    Masked
    sources

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    review Scope
    selected-methods
    paper Trust Assessment
    score
    2
    display Crosses
    2
    scope
    Paper
    status
    assessed
    rating Scale
    library-trust-factor/1-3
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    single
    masking Roles
    participants
    Unblinded
    providers
    Unblinded
    assessors
    Masked
    analysts
    Masked
    basis
    rct
    sources

    https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

    assessed At
    2026-11-02
    review Scope
    selected-methods
    human Approval
    false
    review Limit
    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
    status
    unassessed
    score
    Not recorded
    citation Count
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
    source Revision
    r1-ce11015457b2
    source Content Hash
    ce11015457b240cd0f98b3ee78c6ddc913fd846aaf0c8ef9a04128c44c108575
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
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    level
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    source URLs

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    retrieved At
    2026-11-02
    study Family Id
    publication-36186313
    randomized Study Unit Id
    publication-36186313
    institutions
    None recorded
    institution Evidence
    None recorded
    research Topics

    EMDR

    lab Relevance
    relationship
    inspired-by
    implication
    Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    36186313
    checked At
    2026-11-02T01:32:46.748943+00:00
    pub Types

    research-article · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    EMDR

    record Id
    youth-pmid-36186313
    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-36186313
    title
    Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
    authors
    Azimisefat P, de Jongh A, Rajabi S, Kanske P, Jamshidi F.
    year
    2022
    journal
    Frontiers in psychology
    doi
    10.3389/fpsyg.2022.919148
    pmid
    36186313
    pmcid
    PMC9521642
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    EMDR

    institutions
    None recorded
    institution Evidence
    None recorded
    publication Type

    research-article · Journal Article

    study Family Id
    publication-36186313
    randomized Study Unit Id
    publication-36186313
    existing Repository Matches
    None recorded
    population
    age
    Female adolescents screened at 16–18; arm means around 17.
    age Fit
    target-range
    sample
    45 randomized, 15 per arm.
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Six sessions of EMDR or virtual-reality exposure versus waiting; one-week post-treatment assessment.
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    rct
    category
    randomized-report
    randomization Methods Inspected
    true
    masking
    participants
    Unblinded
    providers
    Unblinded
    assessors
    Masked
    analysts
    Masked
    double Blinding Verified
    false
    proposed Crosses
    2
    approved Crosses
    Not recorded
    findings
    Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
    limitations
    Small female-only sample, short follow-up, self-report outcomes and no active attention control.
    harms And Attrition
    Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
    lab Relevance
    relationship
    inspired-by
    implication
    Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
    1. type
      primary bibliographic record
      url
      https://pubmed.ncbi.nlm.nih.gov/36186313/
      retrieved At
      2026-11-02
      sha256
      e58885ed4699ea3c29620042fbbe55ace07454c8e63f3809f28fcf5c70f6eb03
      hash Scope
      normalized Europe PMC core metadata snapshot
    2. type
      publisher DOI
      url
      https://doi.org/10.3389/fpsyg.2022.919148
      retrieved At
      2026-11-02
    3. type
      PMC article
      url
      https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/
      retrieved At
      2026-11-02
      access
      Full text cached
    4. type
      full-text-xml
      url
      https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML
      retrieved At
      2026-11-02T00:58:52.013199+00:00
      sha256
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      DOI-metadata
      url
      https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148
      retrieved At
      2026-11-02T00:58:52.015691+00:00
      sha256
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    publication Status
    pmid
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    checked At
    2026-11-02T01:32:46.748943+00:00
    pub Types

    research-article · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    None recorded
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
    review
    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
    false
    selected Corpus References
    None recorded
    reference Scope
    Explicit publisher reference identifiers; citation is not proof of inclusion in a meta-analysis.
    content Hash
    ce11015457b240cd0f98b3ee78c6ddc913fd846aaf0c8ef9a04128c44c108575
    revision
    r1-ce11015457b2
    archive Entries
    None recorded
    collection
    vision
    chapter Number
    8
    topic Id
    emdr-youth
    topic Title
    EMDR for youth
    trust Score
    2
evidence
evidence Type
Randomized controlled trial report · single masked role verified
intervention
Six sessions of EMDR or virtual-reality exposure versus waiting; one-week post-treatment assessment.
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
45 randomized, 15 per arm.
population
age
Female adolescents screened at 16–18; arm means around 17.
age Fit
target-range
sample
45 randomized, 15 per arm.
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-36186313
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Relevant to clinically supervised research for specific anxiety problems; not evidence that immersive media alone provides EMDR treatment. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
participants
Unblinded
providers
Unblinded
assessors
Masked
analysts
Masked
harms And Attrition
Not systematically extracted beyond findings/limitations; absence of reporting is not evidence of no harm
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/36186313/ · https://doi.org/10.3389/fpsyg.2022.919148 · https://pmc.ncbi.nlm.nih.gov/articles/PMC9521642/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC9521642/fullTextXML · https://api.crossref.org/works/10.3389%2Ffpsyg.2022.919148

retrieved At
2026-11-02
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    anxiety
    evidence
    1. field
      title
      text
      Efficacy of virtual reality exposure therapy and eye movement desensitization and reprocessing therapy on symptoms of acrophobia and anxiety sensitivity in adolescent girls: A randomized controlled trial.
      matched Text
      anxiety
    2. field
      findings
      text
      Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
      matched Text
      anxiety
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
  2. id
    stress
    evidence
    1. field
      findings
      text
      Both active treatments reduced acrophobia and anxiety sensitivity relative to waiting. Results concern a diagnosed fear-of-heights population rather than general stress reduction.
      matched Text
      stress
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
conditions

anxiety · stress

topic Trust Scores

2

full Text
status
not-indexed
retrieval Available
false

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