Universal Informatics · Research reading room

A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.

Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R. · PLoS medicine · 2023 · Randomized controlled trial report · single masked role verified

Original publication · Original publication · Original publication · Original publication · Original publication

Recorded summary

Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.

Recorded limitations

Selected internet-connected population, short follow-up and cultural setting; intentions are not behaviour.

Evidence and provenance

Chapter Trust Factor uses a minimum of three distinct qualifying studies. Publication records retain their own evidence and assessment.

Study design and assessment
design
Randomized controlled trial report · single masked role verified
assessment
category
single-blind-rct
is Randomized Controlled Trial
true
peer Reviewed
true
basis
Single-blind randomised active-controlled trial
masking Roles
Independent random-number table; participants masked, facilitators unmasked.
sources

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

review Scope
selected-methods
trust Factor
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
single
masking Roles
Independent random-number table; participants masked, facilitators unmasked.
basis
Single-blind randomised active-controlled trial
sources

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
jadad
status
unassessed
score
Not recorded
evidence
evidence Type
Randomized controlled trial report · single masked role verified
intervention
Videos, facilitated group discussion and brochure about help seeking versus general mental-health information
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
144 randomised; 137 completed three-month follow-up
population
age
18–29 LGBTQ+ young adults in China
age Fit
mixed-overlap
sample
144 randomised; 137 completed three-month follow-up
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-36877740
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Tailored inclusive information can support readiness, but assess completed referrals and actual access. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Independent random-number table; participants masked, facilitators unmasked.
harms And Attrition
No adverse events/side effects observed, as reported.
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

retrieved At
2026-11-02
Topics and recorded topic scores
  1. key
    language:black-dog-youth
    title
    Black Dog Institute · Youth research
    collection
    language
    trust Score
    2
  2. key
    language:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    language
    trust Score
    3
  3. key
    language:youth-access-connection
    title
    Youth access, digital support and connection
    collection
    language
    trust Score
    3
Citation snapshot and identifiers
id
youth-pmid-36877740
doi
10.1371/journal.pmed.1004197
pmid
36877740
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
citations By Collection
language
Not recorded
Complete approved library record
lab Relevance
relationship
direct-response
implication
Tailored inclusive information can support readiness, but assess completed referrals and actual access.
transfer Limit
Component evidence does not establish efficacy of the combined Universal Mind lab model.
institutions

Black Dog Institute

institution Evidence
  1. institution
    Black Dog Institute
    basis
    Author affiliation in primary indexed metadata or publisher full text
    evidence
    Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
research Topics

Youth needs / digital / access

publication Status
pmid
36877740
checked At
2026-11-02T01:32:46.754350+00:00
pub Types

Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

indexed Notices
None recorded
crossref Updates
  1. DOI
    10.1371/journal.pmed.1004197
    type
    new_version
    label
    New version
    source
    publisher
    updated
    date-parts
    1. 2023 · 3 · 20

    date-time
    2023-03-20T00:00:00Z
    timestamp
    1679270400000
notice Records
None recorded
scope
Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
notice Summary
Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
randomized Study Unit Id
publication-36877740
publication Approval
status
approved-for-publication
approved By
Ben Korbel
approved At
2026-11-02
assessment
AI assessed; human approved for publication
scope
Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
source Revision
r1-9ad0abbdecfb
source Content Hash
9ad0abbdecfb27d28dc1791eaeaf1608ff1d906122d7073f6592aff018747be2
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

retrieved At
2026-11-02
study Family Id
publication-36877740
approaches

Youth needs / digital / access

id
youth-pmid-36877740
aliases
None recorded
title
A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
journal
PLoS medicine
neurotransmitters
None recorded
year
2023
authors
Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
design
Randomized controlled trial report · single masked role verified
kind
Journal article
identity Conflict
Not recorded
doi
10.1371/journal.pmed.1004197
pmid
36877740
urls

https://doi.org/10.1371/journal.pmed.1004197 · https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

collections

language

categories

Clinical & self-report

targets
None recorded
priority
1
quotes
None recorded
summary
Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
limitation
Selected internet-connected population, short follow-up and cultural setting; intentions are not behaviour.
citation Count
Not recorded
citation Snapshot
count
Not recorded
source
Not recorded
retrieved At
Not recorded
status
not-assessed
study Design Assessment
category
single-blind-rct
is Randomized Controlled Trial
true
peer Reviewed
true
basis
Single-blind randomised active-controlled trial
masking Roles
Independent random-number table; participants masked, facilitators unmasked.
sources

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

review Scope
selected-methods
paper Trust Assessment
score
2
display Crosses
2
scope
Paper
status
assessed
rating Scale
library-trust-factor/1-3
randomized Controlled Trial
true
peer Reviewed
true
blinding
single
masking Roles
Independent random-number table; participants masked, facilitators unmasked.
basis
Single-blind randomised active-controlled trial
sources

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

assessed At
2026-11-02
review Scope
selected-methods
human Approval
false
review Limit
AI source-based design assessment; human content sign-off is recorded separately.
citations By Collection
language
Not recorded
topics
  1. key
    language:black-dog-youth
    title
    Black Dog Institute · Youth research
    collection
    language
    trust Score
    2
  2. key
    language:universal-mind-mobile-lab
    title
    Universal Mind Mobile Lab · Direct response and inspired by
    collection
    language
    trust Score
    3
  3. key
    language:youth-access-connection
    title
    Youth access, digital support and connection
    collection
    language
    trust Score
    3
journal Key
plosmedicine
journal Label
PLoS medicine
chapter Entries
  1. id
    language-black-dog-youth-youth-pmid-36877740
    aliases
    None recorded
    title
    A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
    authors
    Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
    year
    2023
    journal
    PLoS medicine
    doi
    10.1371/journal.pmed.1004197
    pmid
    36877740
    urls

    https://doi.org/10.1371/journal.pmed.1004197 · https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

    collections

    language

    categories

    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · depression

    condition Evidence
    1. id
      anxiety
      evidence
      1. field
        findings
        text
        Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
        matched Text
        anxiety
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    2. id
      depression
      evidence
      1. field
        findings
        text
        Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
        matched Text
        depression
      scope
      Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
    age Groups

    youth · adults

    age Population
    record Id
    youth-pmid-36877740
    collections

    language

    groups

    youth · adults

    reported Ages
    18–29 LGBTQ+ young adults in China
    youth Scope
    included
    youth Source Note
    The existing youth filter includes adolescents and source-defined young people. It does not establish a separate 16–24 estimate.
    age Fit
    mixed-overlap
    source URL
    https://pubmed.ncbi.nlm.nih.gov/36877740/
    basis Type
    selected-methods-ai-editorial-assessment
    classification Note
    Broad groups describe source-reported populations or review scope. Eligibility and study mean ages are not observed participant ranges; read the reported-age wording.
    community Matches
    None recorded
    kind
    Journal article
    design
    Randomized controlled trial report · single masked role verified
    origin
    approved-youth-20261102
    priority
    1
    quotes
    None recorded
    finding
    Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
    summary
    Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
    limitation
    Selected internet-connected population, short follow-up and cultural setting; intentions are not behaviour.
    evidence
    evidence Type
    Randomized controlled trial report · single masked role verified
    intervention
    Videos, facilitated group discussion and brochure about help seeking versus general mental-health information
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    sample
    144 randomised; 137 completed three-month follow-up
    population
    age
    18–29 LGBTQ+ young adults in China
    age Fit
    mixed-overlap
    sample
    144 randomised; 137 completed three-month follow-up
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    measurement
    Specific outcomes are reported in the finding and retained appraisal.
    trial Id
    publication-36877740
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    relationship Note
    Tailored inclusive information can support readiness, but assess completed referrals and actual access. Component evidence does not establish efficacy of the combined Universal Mind lab model.
    measured Genes
    None recorded
    pathways
    None recorded
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    masking Roles
    Independent random-number table; participants masked, facilitators unmasked.
    harms And Attrition
    No adverse events/side effects observed, as reported.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

    retrieved At
    2026-11-02
    study Design Assessment
    category
    single-blind-rct
    is Randomized Controlled Trial
    true
    peer Reviewed
    true
    basis
    Single-blind randomised active-controlled trial
    masking Roles
    Independent random-number table; participants masked, facilitators unmasked.
    sources

    https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

    review Scope
    selected-methods
    paper Trust Assessment
    score
    2
    display Crosses
    2
    scope
    Paper
    status
    assessed
    rating Scale
    library-trust-factor/1-3
    randomized Controlled Trial
    true
    peer Reviewed
    true
    blinding
    single
    masking Roles
    Independent random-number table; participants masked, facilitators unmasked.
    basis
    Single-blind randomised active-controlled trial
    sources

    https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

    assessed At
    2026-11-02
    review Scope
    selected-methods
    human Approval
    false
    review Limit
    AI source-based design assessment; human content sign-off is recorded separately.
    jadad
    status
    unassessed
    score
    Not recorded
    citation Count
    Not recorded
    citation Snapshot
    count
    Not recorded
    source
    Not recorded
    retrieved At
    Not recorded
    status
    not-assessed
    publication Approval
    status
    approved-for-publication
    approved By
    Ben Korbel
    approved At
    2026-11-02
    assessment
    AI assessed; human approved for publication
    scope
    Approved research summaries for Informatics staging. No clinical peer review, treatment recommendation, partner endorsement or production release is claimed.
    source Revision
    r1-9ad0abbdecfb
    source Content Hash
    9ad0abbdecfb27d28dc1791eaeaf1608ff1d906122d7073f6592aff018747be2
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    level
    selected-methods
    source URLs

    https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

    retrieved At
    2026-11-02
    study Family Id
    publication-36877740
    randomized Study Unit Id
    publication-36877740
    institutions

    Black Dog Institute

    institution Evidence
    1. institution
      Black Dog Institute
      basis
      Author affiliation in primary indexed metadata or publisher full text
      evidence
      Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
    research Topics

    Youth needs / digital / access

    lab Relevance
    relationship
    direct-response
    implication
    Tailored inclusive information can support readiness, but assess completed referrals and actual access.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    publication Status
    pmid
    36877740
    checked At
    2026-11-02T01:32:46.754350+00:00
    pub Types

    Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    1. DOI
      10.1371/journal.pmed.1004197
      type
      new_version
      label
      New version
      source
      publisher
      updated
      date-parts
      1. 2023 · 3 · 20

      date-time
      2023-03-20T00:00:00Z
      timestamp
      1679270400000
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    approaches

    Youth needs / digital / access

    record Id
    youth-pmid-36877740
    source Pages
    None recorded
    assessment Record
    id
    youth-pmid-36877740
    title
    A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
    authors
    Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
    year
    2023
    journal
    PLoS medicine
    doi
    10.1371/journal.pmed.1004197
    pmid
    36877740
    pmcid
    PMC10027204
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    Youth needs / digital / access

    institutions

    Black Dog Institute

    institution Evidence
    1. institution
      Black Dog Institute
      basis
      Author affiliation in primary indexed metadata or publisher full text
      evidence
      Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
    publication Type

    Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

    study Family Id
    publication-36877740
    randomized Study Unit Id
    publication-36877740
    existing Repository Matches
    None recorded
    population
    age
    18–29 LGBTQ+ young adults in China
    age Fit
    mixed-overlap
    sample
    144 randomised; 137 completed three-month follow-up
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Videos, facilitated group discussion and brochure about help seeking versus general mental-health information
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    Single-blind randomised active-controlled trial
    category
    randomized-report
    randomization Methods Inspected
    true
    masking
    Independent random-number table; participants masked, facilitators unmasked.
    double Blinding Verified
    false
    proposed Crosses
    2
    approved Crosses
    Not recorded
    findings
    Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
    limitations
    Selected internet-connected population, short follow-up and cultural setting; intentions are not behaviour.
    harms And Attrition
    No adverse events/side effects observed, as reported.
    lab Relevance
    relationship
    direct-response
    implication
    Tailored inclusive information can support readiness, but assess completed referrals and actual access.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
    1. type
      primary bibliographic record
      url
      https://pubmed.ncbi.nlm.nih.gov/36877740/
      retrieved At
      2026-11-02
      sha256
      006b1675c6642e58919af3b7ebf1614b08bd725bebeb13f781fdf5b422d7bbc7
      hash Scope
      normalized Europe PMC core metadata snapshot
    2. type
      publisher DOI
      url
      https://doi.org/10.1371/journal.pmed.1004197
      retrieved At
      2026-11-02
    3. type
      PMC article
      url
      https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/
      retrieved At
      2026-11-02
      access
      Full text cached
    4. type
      full-text-xml
      url
      https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML
      retrieved At
      2026-11-02T00:58:56.116701+00:00
      sha256
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    5. type
      DOI-metadata
      url
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      retrieved At
      2026-11-02T00:58:57.380161+00:00
      sha256
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    publication Status
    pmid
    36877740
    checked At
    2026-11-02T01:32:46.754350+00:00
    pub Types

    Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    1. DOI
      10.1371/journal.pmed.1004197
      type
      new_version
      label
      New version
      source
      publisher
      updated
      date-parts
      1. 2023 · 3 · 20

      date-time
      2023-03-20T00:00:00Z
      timestamp
      1679270400000
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
    review
    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
    false
    selected Corpus References
    None recorded
    reference Scope
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    trust Score
    2
  2. id
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    aliases
    None recorded
    title
    A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
    authors
    Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
    year
    2023
    journal
    PLoS medicine
    doi
    10.1371/journal.pmed.1004197
    pmid
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    language

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    Clinical & self-report

    targets
    None recorded
    neurotransmitters
    None recorded
    conditions

    anxiety · depression

    condition Evidence
    1. id
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      1. field
        findings
        text
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        matched Text
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        text
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    classification Note
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    Journal article
    design
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    origin
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    1
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    None recorded
    finding
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    evidence Type
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    Videos, facilitated group discussion and brochure about help seeking versus general mental-health information
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    relationship Note
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    measured Genes
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    None recorded
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    qualified
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    Independent random-number table; participants masked, facilitators unmasked.
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    retrieved At
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    true
    peer Reviewed
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    approved-for-publication
    approved By
    Ben Korbel
    approved At
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    assessment
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    retrieved At
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    1. institution
      Black Dog Institute
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      Author affiliation in primary indexed metadata or publisher full text
      evidence
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    relationship
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    pub Types

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    indexed Notices
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      date-parts
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      date-time
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    notice Records
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    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
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    Youth needs / digital / access

    record Id
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    source Pages
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    assessment Record
    id
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    title
    A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
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    Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
    year
    2023
    journal
    PLoS medicine
    doi
    10.1371/journal.pmed.1004197
    pmid
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    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    Youth needs / digital / access

    institutions

    Black Dog Institute

    institution Evidence
    1. institution
      Black Dog Institute
      basis
      Author affiliation in primary indexed metadata or publisher full text
      evidence
      Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
    publication Type

    Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

    study Family Id
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    existing Repository Matches
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    population
    age
    18–29 LGBTQ+ young adults in China
    age Fit
    mixed-overlap
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    144 randomised; 137 completed three-month follow-up
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    notice Records
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    scope
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    trust Score
    3
  3. id
    language-youth-access-connection-youth-pmid-36877740
    aliases
    None recorded
    title
    A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
    authors
    Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
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    collections

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    categories

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    targets
    None recorded
    neurotransmitters
    None recorded
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      1. field
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        text
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    relationship Note
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    pathways
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    unassessed
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    Not recorded
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    count
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    Not recorded
    retrieved At
    Not recorded
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    retrieved At
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    1. institution
      Black Dog Institute
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      evidence
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    2026-11-02T01:32:46.754350+00:00
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    indexed Notices
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    crossref Updates
    1. DOI
      10.1371/journal.pmed.1004197
      type
      new_version
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      publisher
      updated
      date-parts
      1. 2023 · 3 · 20

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      1679270400000
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
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    Youth needs / digital / access

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    source Pages
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    assessment Record
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    A multicomponent digital intervention to promote help-seeking for mental health problems and suicide in sexual and gender diverse young adults: A randomized controlled trial.
    authors
    Han M, Wang Y, Zhang Y, Wang Y, Ou J, Ren D, Cai C, Liu K, Li R, Han J, Chen R.
    year
    2023
    journal
    PLoS medicine
    doi
    10.1371/journal.pmed.1004197
    pmid
    36877740
    pmcid
    PMC10027204
    trial Registries
    None recorded
    registry Scope
    Identifiers explicitly reported in article abstract; other registrations remain unverified
    collection
    youth-20261102
    topics

    Youth needs / digital / access

    institutions

    Black Dog Institute

    institution Evidence
    1. institution
      Black Dog Institute
      basis
      Author affiliation in primary indexed metadata or publisher full text
      evidence
      Black Dog Institute, University of New South Wales, Sydney, NSW, Australia.
    publication Type

    Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

    study Family Id
    publication-36877740
    randomized Study Unit Id
    publication-36877740
    existing Repository Matches
    None recorded
    population
    age
    18–29 LGBTQ+ young adults in China
    age Fit
    mixed-overlap
    sample
    144 randomised; 137 completed three-month follow-up
    setting
    Not separately established; see population/intervention description
    community
    Not assigned
    intervention
    description And Dose
    Videos, facilitated group discussion and brochure about help seeking versus general mental-health information
    provider
    Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
    comparator
    See design/intervention description; otherwise unknown
    design
    description
    Single-blind randomised active-controlled trial
    category
    randomized-report
    randomization Methods Inspected
    true
    masking
    Independent random-number table; participants masked, facilitators unmasked.
    double Blinding Verified
    false
    proposed Crosses
    2
    approved Crosses
    Not recorded
    findings
    Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
    limitations
    Selected internet-connected population, short follow-up and cultural setting; intentions are not behaviour.
    harms And Attrition
    No adverse events/side effects observed, as reported.
    lab Relevance
    relationship
    direct-response
    implication
    Tailored inclusive information can support readiness, but assess completed referrals and actual access.
    transfer Limit
    Component evidence does not establish efficacy of the combined Universal Mind lab model.
    source Access
    scope
    selected-methods
    full Text Cached
    true
    methods Inspected
    true
    full Text Appraisal Claim
    false
    sources
    1. type
      primary bibliographic record
      url
      https://pubmed.ncbi.nlm.nih.gov/36877740/
      retrieved At
      2026-11-02
      sha256
      006b1675c6642e58919af3b7ebf1614b08bd725bebeb13f781fdf5b422d7bbc7
      hash Scope
      normalized Europe PMC core metadata snapshot
    2. type
      publisher DOI
      url
      https://doi.org/10.1371/journal.pmed.1004197
      retrieved At
      2026-11-02
    3. type
      PMC article
      url
      https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/
      retrieved At
      2026-11-02
      access
      Full text cached
    4. type
      full-text-xml
      url
      https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML
      retrieved At
      2026-11-02T00:58:56.116701+00:00
      sha256
      5564c968d0cc405b678681cad25487dbfcaefe257150de5d8b94c6ba54b3daf3
    5. type
      DOI-metadata
      url
      https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197
      retrieved At
      2026-11-02T00:58:57.380161+00:00
      sha256
      959a3d849fc16f37e18e0402158ae700de1cce1ee40b5c36e4118c0dc6bd9017
    publication Status
    pmid
    36877740
    checked At
    2026-11-02T01:32:46.754350+00:00
    pub Types

    Research Support, Non-U.S. Gov't · research-article · Randomized Controlled Trial · Journal Article

    indexed Notices
    None recorded
    crossref Updates
    1. DOI
      10.1371/journal.pmed.1004197
      type
      new_version
      label
      New version
      source
      publisher
      updated
      date-parts
      1. 2023 · 3 · 20

      date-time
      2023-03-20T00:00:00Z
      timestamp
      1679270400000
    notice Records
    None recorded
    scope
    Europe PMC indexed publication types/linked notices, publisher JATS related articles and Crossref update-to metadata; absence is not a guarantee of no notice.
    notice Summary
    Indexed related notices are retained below; no retraction identified in this bounded metadata check. This is not an exhaustive guarantee.
    quality
    tier
    qualified
    qualification
    Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
    formal Risk Of Bias Tool Applied
    false
    jadad Score
    Not recorded
    review Ready
    true
    hold Reason
    Not recorded
    duplicate Of
    Not recorded
    review
    status
    pending
    reviewer
    Not recorded
    approved At
    Not recorded
    decision Scope
    Ben reviews proposed content and release; full medical-paper reading is not required.
    provenance
    Discovered and appraised by AI; pending human content sign-off
    production Eligible
    false
    approved Retrieval Eligible
    false
    selected Corpus References
    None recorded
    reference Scope
    Explicit publisher reference identifiers; citation is not proof of inclusion in a meta-analysis.
    content Hash
    9ad0abbdecfb27d28dc1791eaeaf1608ff1d906122d7073f6592aff018747be2
    revision
    r1-9ad0abbdecfb
    archive Entries
    None recorded
    collection
    language
    chapter Number
    6
    topic Id
    youth-access-connection
    topic Title
    Youth access, digital support and connection
    trust Score
    3
evidence
evidence Type
Randomized controlled trial report · single masked role verified
intervention
Videos, facilitated group discussion and brochure about help seeking versus general mental-health information
provider
Not separately established; clinician/teacher/app details, if known, are retained in the intervention description
comparator
See design/intervention description; otherwise unknown
sample
144 randomised; 137 completed three-month follow-up
population
age
18–29 LGBTQ+ young adults in China
age Fit
mixed-overlap
sample
144 randomised; 137 completed three-month follow-up
setting
Not separately established; see population/intervention description
community
Not assigned
measurement
Specific outcomes are reported in the finding and retained appraisal.
trial Id
publication-36877740
trial Registries
None recorded
registry Scope
Identifiers explicitly reported in article abstract; other registrations remain unverified
relationship Note
Tailored inclusive information can support readiness, but assess completed referrals and actual access. Component evidence does not establish efficacy of the combined Universal Mind lab model.
measured Genes
None recorded
pathways
None recorded
quality
tier
qualified
qualification
Qualified for the stated design-specific use in a rapid methods-based review, not necessarily low risk of bias or high certainty.
formal Risk Of Bias Tool Applied
false
jadad Score
Not recorded
masking Roles
Independent random-number table; participants masked, facilitators unmasked.
harms And Attrition
No adverse events/side effects observed, as reported.
source Access
scope
selected-methods
full Text Cached
true
methods Inspected
true
full Text Appraisal Claim
false
level
selected-methods
source URLs

https://pubmed.ncbi.nlm.nih.gov/36877740/ · https://doi.org/10.1371/journal.pmed.1004197 · https://pmc.ncbi.nlm.nih.gov/articles/PMC10027204/ · https://www.ebi.ac.uk/europepmc/webservices/rest/PMC10027204/fullTextXML · https://api.crossref.org/works/10.1371%2Fjournal.pmed.1004197

retrieved At
2026-11-02
jadad
status
unassessed
score
Not recorded
condition Evidence
  1. id
    anxiety
    evidence
    1. field
      findings
      text
      Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
      matched Text
      anxiety
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
  2. id
    depression
    evidence
    1. field
      findings
      text
      Help-seeking intentions and literacy improved; actual help seeking, self-stigma, depression and anxiety did not significantly improve.
      matched Text
      depression
    scope
    Studied topic or reported outcome, including null findings; no diagnosis, benefit or subgroup membership is inferred.
conditions

anxiety · depression

topic Trust Scores

2 · 3

full Text
status
not-indexed
retrieval Available
false

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