GENOMICS
From transcription to the research data.
Transcription factors bind to locations on DNA and help regulate gene expression. Explore the process, inspect the binding-site data and read the research.
Sound Atlas
POSSIBLE FIBONACCI STRUCTURES
Explore the evidence for music, auditory stimulation and molecular responses.
SEQUENCE STRUCTURE
RELATIONSHIP
MUSIC ATLAS · MEASUREMENT ARCHITECTURE
Validating the research approach for stakeholders before a substantial investment in mRNA sequencing.
Our hypothesis: does electronic music modulate OXTR via Fibonacci numbers? Our initial non-invasive study, N = 33, brings physiology, audience experience and musical structure together to validate the research approach and establish the case for mRNA sequencing investment.
These graphics are visual mockups of a real Universal Informatics Music Atlas Python script: custom software Ben Korbel is developing with Gemini to measure and unify these metrics together as one. Implementation is in progress.
EEG from Muse S Athena, galvanic skin response (GSR / EDA), heart-rate variability, HRV power spectral density (PSD) and baroreflex sensitivity. Brain-state analysis brings amplitude and phase–amplitude coupling onto the shared timeline.
A 400-channel laboratory hyperspectral analysis and smartphone-grade RGB analysis reconstructed into 31 spectral bands. Inferred oxytocin is an exploratory model output created by Immersion Neuroscience via research with DARPA. Explore Immersion Neuroscience ↗ and SIX ↗.
Continuous audience feedback and a participant peak-moment trigger, aligned with real-time song analysis: position within a 64-bar sequence, melodic anticipation and resolution, chords, arpeggios, and Fibonacci / Pisano landmarks.
The landscape overview brings the streams together, from EEG at the top to Fibonacci coding at the bottom.
Brain state, amplitude and coupling alongside audience peaks, cardiovascular features and spectral imaging.
The vertical view begins with EEG and aligns the measurement streams around an audience-reported peak moment.
NEXT STAGE · mRNA SEQUENCING
Following validation of the research approach through the N = 33 non-invasive study, we will invest in mRNA sequencing through the Kinghorn Centre for Clinical Genomics at the Garvan Institute of Medical Research ↗, from whom we have received a commercial quote.
mRNA sequencing represents an investment of A$600–A$1,000 per participant. The initial non-invasive phase establishes the case for that investment for stakeholders. Sequencing will compare OXTR mRNA expression in samples collected before and after the intervention or song.
Vision Atlas
Explore visual and ocular biology, light exposure, gene expression and the EMDR literature.
Research comparison · hypothesis under investigation
Are hexagonal animations more natural, human, and impactful for EMDR visual stimulation than traditional horizontal tracking green lights? We use the honeycomb conjecture as inspiration, where hexagonal packing is nature's most efficient division of space. Furthermore, many endogenous neurotransmitters, hormones, and nucleic bases natively utilise hexagonal configurations within their molecular architecture.
We hypothesise that a hexagonally structured saccadic tracking pattern imposes a distinct oculomotor and visual psychophysics load compared to standard linear tracking. We propose that the complex coordination required to navigate this geometric pattern optimises retinal and visual pathway signalling, thereby driving a downstream biological response that upregulates OXTR gene transcription (measured via mRNA sequencing) and enhances emotional regulation.
Language Atlas
From mantra and meditation to communication, psychotherapy and epigenomics.
Explore the original Mantra collection alongside recent molecular and clinical research.
Active recitation, mental practice and mindfulness, with gene expression, methylation and physiological outcomes identified separately.
Research on psychotherapy and molecular change, including trauma-focused therapy, cognitive behavioural therapy and narrative exposure.
A developing research question: how do interpersonal experiences relate to our epigenome? Whole-treatment associations remain distinct from effects of particular words.
Partners
Our research uses Wolfram for mathematical verification and Biopython for sequence analysis. OpenAI’s GPT and Google DeepMind’s Gemini support research exploration and development.
We are committed to open, transparent research, reproducible methods and sharing knowledge for the benefit of humankind.
A preliminary list of organisations and research communities we aspire to collaborate with:
Youth mental health research, early intervention and digital innovation.
Genomics, sequencing, bioinformatics and medical research.
Bioinformatics and computer vision.
Molecular research infrastructure and shared biological datasets.
Bioinformatics tools, reproducible workflows and research collaboration.
Discoverable, accessible and reusable research data.
Discovering research studies and sharing descriptions of future datasets.
Molecular data and models for mental health research.
Genetic evidence for understanding mental health conditions.
Brain gene expression and regulation, with relevance to our OXTR research.
Accessible molecular evidence for mental health research.
Molecular biomarkers for mental health.
Circadian rhythms, brain models and bipolar disorder research.
Computer vision, artificial intelligence and physics modelling.
About
Bioinformatics platform for mental health
Investigating potential relationships between the Fibonacci sequence and OXTR gene expression.
Does modular compression reveal statistically significant patterns, or merely mathematical elegance?
Do the nested sequences within Fibonacci Pisano periods have biological and molecular implications?
Inspired by research into how geometric architectures and Fibonacci-ordered dynamics can protect quantum information, we are investigating whether geometry derived from Fibonacci Pisano periods can improve the computational efficiency of hyperspectral image analysis for genomics.
Science Advances · 2015
Toroidal geometry in neural activityNature · 2022
Science and Open QuestionsIf independent studies verify biological significance in the OXTR–Fibonacci relationship, we plan to extend the investigation to a wider set of candidate genes and molecular systems.
Wolfram is our planned primary computational environment for symbolic geometry and future bioinformatic research.